摘要
目的:探讨布地奈德联合复方异丙托溴铵治疗小儿肺炎支原体感染后咳嗽的临床效果。方法:选择2017年9月—2018年9月在我院治疗的肺炎支原体感染后咳嗽患儿98例,随机分为两组,每组各49例。对照组给予复方异丙托溴铵雾化吸入,观察组在对照组基础上联合使用布地奈德雾化吸入,比较两组咳嗽症状评分、各症状消除时间与住院时间、不良反应发生率及临床治疗总有效率。结果:观察组不良反应发生率略高于对照组,但差异无统计学意义(P>0.05);观察组治疗后各时间段咳嗽症状评分均低于对照组,差异有统计学意义(P<0.05);观察组总有效率高于对照组,差异有统计学意义(P<0.05),观察组各症状消除时间及住院时间均短于对照组,差异有统计学意义(P<0.05)。结论:小儿肺炎支原体感染后咳嗽使用布地奈德联合复方异丙托溴铵联合治疗,能够对咳嗽症状起到良好的改善作用,同时可在一定程度上缩短其康复时间,临床疗效确切。
Objective: To study the clinical effect of budesonide combined with compound isoproterenol in the treatment of children with mycoplasma pneumoniae infection. Methods: 98 children with mycoplasma infection treated in our hospital from September 2017 to September 2018 were randomly divided into 2 groups, and 49 cases in each group. In the control group, the compound isoprotomidine was given in the control group. The observation group combined with budesonide for inhalation on the basis of the control. The cough symptom scores, the time of elimination of each symptom, the time of hospitalization, the incidence of adverse reactions and the total effective rate of the clinical treatment between the two groups were compared. Results: The incidence of adverse reaction in the observation group was slightly higher than that of the control group, but The difference was not significant (P>0.05), and the symptoms of cough in the observation group were lower than that in the control group (P <0.05), and the total effective rate of the observation group was higher than that of the control group. The difference was statistically significant (P <0.05). The time of elimination and the time of hospital stay in the observation group were shorter than that in the control group (P <0.05). Conclusion: The combination of budesonide and budesonide combined with budesonide combined with the combination of budesonide and budesonide can improve the symptoms of cough, and can shorten the recovery time to a certain extent, and the clinical curative effect is definite.
作者
费进军
FEI Jin-jun(The Paediatric 332100, the People's Hospital of the People's Hospital of the Qaidam District, Jiujiang Jiangxi 332100,China)
出处
《药品评价》
CAS
2019年第6期42-44,共3页
Drug Evaluation
基金
江西省卫生计生委科技计划项目
编号:20167145
关键词
小儿肺炎支原体感染
咳嗽:布地奈德
复方异丙托溴铵
咳嗽症状
Mycoplasma Pneumoniae Infection in Children
Cough
Budesonide
Compound Ipratropium Bromide
Cough Symptoms