期刊文献+

布地奈德联合复方异丙托溴铵治疗小儿肺炎支原体感染后咳嗽临床效果评估 被引量:16

Clinical Evaluation of Budesonide Combined with Compound Ipratropium Bromide in the Treatment of Cough after Mycoplasma Pneumoniae Infection in Children
暂未订购
导出
摘要 目的:探讨布地奈德联合复方异丙托溴铵治疗小儿肺炎支原体感染后咳嗽的临床效果。方法:选择2017年9月—2018年9月在我院治疗的肺炎支原体感染后咳嗽患儿98例,随机分为两组,每组各49例。对照组给予复方异丙托溴铵雾化吸入,观察组在对照组基础上联合使用布地奈德雾化吸入,比较两组咳嗽症状评分、各症状消除时间与住院时间、不良反应发生率及临床治疗总有效率。结果:观察组不良反应发生率略高于对照组,但差异无统计学意义(P>0.05);观察组治疗后各时间段咳嗽症状评分均低于对照组,差异有统计学意义(P<0.05);观察组总有效率高于对照组,差异有统计学意义(P<0.05),观察组各症状消除时间及住院时间均短于对照组,差异有统计学意义(P<0.05)。结论:小儿肺炎支原体感染后咳嗽使用布地奈德联合复方异丙托溴铵联合治疗,能够对咳嗽症状起到良好的改善作用,同时可在一定程度上缩短其康复时间,临床疗效确切。 Objective: To study the clinical effect of budesonide combined with compound isoproterenol in the treatment of children with mycoplasma pneumoniae infection. Methods: 98 children with mycoplasma infection treated in our hospital from September 2017 to September 2018 were randomly divided into 2 groups, and 49 cases in each group. In the control group, the compound isoprotomidine was given in the control group. The observation group combined with budesonide for inhalation on the basis of the control. The cough symptom scores, the time of elimination of each symptom, the time of hospitalization, the incidence of adverse reactions and the total effective rate of the clinical treatment between the two groups were compared. Results: The incidence of adverse reaction in the observation group was slightly higher than that of the control group, but The difference was not significant (P>0.05), and the symptoms of cough in the observation group were lower than that in the control group (P <0.05), and the total effective rate of the observation group was higher than that of the control group. The difference was statistically significant (P <0.05). The time of elimination and the time of hospital stay in the observation group were shorter than that in the control group (P <0.05). Conclusion: The combination of budesonide and budesonide combined with budesonide combined with the combination of budesonide and budesonide can improve the symptoms of cough, and can shorten the recovery time to a certain extent, and the clinical curative effect is definite.
作者 费进军 FEI Jin-jun(The Paediatric 332100, the People's Hospital of the People's Hospital of the Qaidam District, Jiujiang Jiangxi 332100,China)
出处 《药品评价》 CAS 2019年第6期42-44,共3页 Drug Evaluation
基金 江西省卫生计生委科技计划项目 编号:20167145
关键词 小儿肺炎支原体感染 咳嗽:布地奈德 复方异丙托溴铵 咳嗽症状 Mycoplasma Pneumoniae Infection in Children Cough Budesonide Compound Ipratropium Bromide Cough Symptoms
  • 相关文献

参考文献11

二级参考文献143

  • 1郁志伟,谢娟娟.喘息性支气管炎和支气管哮喘的相关性研究[J].实用儿科临床杂志,2005,20(4):329-329. 被引量:28
  • 2陈志远,张志浩,车审言,马国宣,黄京慧,袁扬,陈刚,李艳军,段建勇.规范的大容量肺灌洗术治疗尘肺病[J].中华医学杂志,2005,85(40):2856-2858. 被引量:85
  • 3陈杰,张江义,鲁翠红.布地奈德联合沙丁胺醇雾化吸入对支气管哮喘急性发作的疗效观察[J].临床肺科杂志,2007,12(10):1077-1078. 被引量:60
  • 4胡亚美 江载芳.诸福棠实用儿科学[M]第7版[M].北京:人民卫生出版社,2002.1514.
  • 5Chen CJ,Juan CJ,Hsu ML,et al.Mycoplasma pneumonia infection presenting as neutropenia thrombocytopenia and acute hepatitis in a child[J].J Microbial Immune Infect,2004,37(2):128-130.
  • 6Tamura A,Matsubara K,Tanaka T,et al.Methylprednisolone pulse therapy for refractory Mycoplasma pneumoniae pneumonia in children[J].J Infect,2008,57(3):223-228.
  • 7Specjalski K,Jassem E.Chlamydophila pneumoniae,Mycoplasma pneumoniae infections,and asthma control[J].Allergy Asthma Proc,2011,32(2):923-926.
  • 8Cao B,Zhao CJ,Yin YD,et al.High prevalence of macrolide resistance in Mycoplasma pneumoniae isolates from adult and adolescent patients with respiratory tract infection in China[J].Clin Infect Dis,2010,51(2):189-194.
  • 9Chironna M,Sallustio A,Esposito S,et al.Emergence of macrolide-resistant strains during an outbreak of Mycoplasma pneumoniae infections in children[J].J Antimicrob Chemother,2011,66(4):734-737.
  • 10Yang A, Kang B, Choi SY, et al. Acute necrotizing pancreatitis associated with mycoplasma pneumonia infection in a child [J]. Pediatric gastroenterology, hepatology & nutrition, 2015, 18 ( 3 ) : 209 -215.

共引文献397

同被引文献170

引证文献16

二级引证文献62

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部