摘要
目的:探讨影响他汀类药物依从性的影响因素。方法:计算机检索中国期刊全文专题数据库、万方电子期刊、中国科技期刊数据库,查找在国内发表的有关他汀类药物依从性影响因素的文献,采用RevMan5.3对符合条件的文献进行分析。结果:共有11篇文献纳入研究,包含他汀类用药患者3733人,1676名患者依从性差。从中摘录出11项影响因素(患者性别、患者年龄、文化程度、地域来源、医疗费用、药物知识、疾病知识、医患关系、不良反应、患病时程和用药时间)并进行二分类,发现患者性别和药物不良反应不会影响他汀类药物的依从性。而年龄越大、文化程度越低、来自乡村、自费医疗、对药物和疾病不了解、病程和用药时间长、医患关系较差这些因素均会使他汀类药物的依从性降低。结论:医师和药师应加强对患者的用药教育,强调依从用药的重要性,同时国家应增加对农村地区患者的药费报销比例,提高患者用药的依从性。
Objective: To investigate the factors influencing the compliance to statins. Methods: Searching Chinese Journal Full-text database, Wanfang Database and Chinese Scientific Journal Full-text Database, the meta-analysis was performed using RevMan 5.3 software. Results: 11 articles including 3733 patients (1676 patients with poor medical compliance) were included for meta-analysis. 11 factors were abstracted form the articles, including the patient's gender, age, education, districts, medical expenses, medication knowledge, knowledge of the disease, the doctor-patient relationship, adverse reactions, course of disease and medication time. Except gender and adverse reactions, other factors could influence the patients' compliance. Conclusion: To improve the patients' compliance, drug education was a very important method for physicians and pharmacists;moreover, the reimbursement of medical expense to peasant should be increased.
作者
杜鹏强
王爱凤
马永成
李国峰
李新刚
DU Peng-qiang;WANG Ai-feng;MA Yong-cheng;LI Guo-feng;LI Xin-gang(Fuwai Central China Cardiovascular Hospital, Zhengzhou Henan 450003, China;Beijing Tiantan Hospital, Capital Medical University, Beijing100070, China)
出处
《药品评价》
CAS
2019年第6期6-12,共7页
Drug Evaluation
基金
"神经系统药物治疗"
北京市医院管理局扬帆计划
编号:ZYLX201827
