摘要
目的探讨对小儿重症肺炎患者选择小剂量多巴胺+多巴酚丁胺治疗后获得的临床效果。方法选择该院2016年11月—2018年5月收治的66例小儿重症肺炎患者作为实验对象;随机数表法分组后明确各组所用药物;对照组(33例):选择常规疗法完成;观察组(33例):选择常规疗法+小剂量多巴胺+多巴酚丁胺药物完成;观察对比两组小儿重症肺炎患者的用药效果(显效率、总有效率)、症状消失时间(呼吸困难缓解时间、体温消退时间、啰音消失时间、心率恢复正常时间)、血气分析指标(PaO2水平、HCO_3-水平、PaCO_2)。结果观察组显效患者24例(72.73%),有效患者7例(21.21%),无效患者2例(6.06%),总有效患者31例(93.94%),对照组显效患者15例(45.45%),有效患者8例(24.24%),无效患者10例(30.30%),总有效患者23例(69.70%);同对照组小儿重症肺炎患者用药效果(45.45%)、(69.70%)对比,观察组在显效率(72.73%)以及总有效率(93.94%)两方面均获明显提升(χ~2=5.076 9,6.518 5,P<0.05);同对照组小儿重症肺炎患者症状消失时间对比,观察组呼吸困难缓解时间、体温消退时间、啰音消失时间以及心率恢复正常时间对比,观察组均获明显缩短(t=4.070 9,4.455 8,9.021 7,5.113 5,P<0.05)。同对照组小儿重症肺炎患者血气分析结果对比,观察组PaO_2水平以及HCO_3-水平均获明显提升,PaCO2水平获明显降低(t=2.869 1,3.925 9,2.680 4,P<0.05)。结论小儿重症肺炎患者在接受治疗期间,小剂量多巴胺+多巴酚丁胺药物的联合应用,对于患儿用药显效率、总有效率提升,症状消失时间缩短以及血气分析指标改善,效果显著,最终对于小儿重症肺炎患者的病情康复,奠定基础。
Objective To investigate the clinical effects of low-dose dopamine + dobutamine in patients with severe pneumonia. Methods Sixty-six patients with severe pneumonia in our hospital from November 2016 to May 2018 were selected as experimental subjects.The drugs used in each group were identified by random number table method. The control group(33 cases): routine therapy was selected. Observation group(33 cases): the choice of conventional therapy + low-dose dopamine + dobutamine drug was completed;observed the contrast between the two groups of children with severe pneumonia(effectiveness, total efficiency), symptom disappearance time(dyspnea relief), body temperature regression time, voice disappearance time, heart rate return to normal time, blood gas analysis index(PaO2 level, HCO3-level, PaCO2). Results In the observation group, 24 patients(72.73%) were effective, 7 patients(21.21%)were effective, 2 patients(6.06%) were ineffective, 31 patients(93.94%) were effective, and 15 patients were effective in the controlgroup(45.45%), 8 patients(24.24%) were effective, 10 patients(30.30%) were ineffective, and 23 patients(69.70%) were effective.Compared with the control group(45.45%) and(69.70%) of children with severe pneumonia in the control group, the observation group was significantly improved in both the effective rate(72.73%) and the total effective rate(93.94%)(χ^2=5.076 9, 6.518 5,P<0.05). Compared with the control group, the symptoms disappeared in children with severe pneumonia, and the observation group of breathing difficulty relief time, body temperature regression time, voice disappearance time and heart rate return to normal time were compared, and the observation group was significantly shortened(t=4.070 9, 4.455 8, 9.021 7, 5.113 5,P<0.05). Compared with the blood gas analysis results of children with severe pneumonia in the control group, the PaO2 level and HCO3 level in the observation group were significantly improved, and the PaCO2 level was significantly decreased(t=2.869 1, 3.925 9, 2.680 4,P<0.05). Conclusion The combination of low-dose dopamine and dobutamine in patients with severe pneumonia in children has a significant effect on the efficiency, total efficiency, shortening of symptoms disappearance and blood gas analysis indicators, finally, laying the foundation for the recovery of patients with severe pneumonia in children.
作者
周永芳
ZHOU Yong-fang(Yuxi Children's Hospital, Yuxi, Yunnan Province, 653100 China)
出处
《世界复合医学》
2019年第1期58-60,共3页
World Journal of Complex Medicine
