摘要
PM2.5的化学成分极其复杂,可携带部分病毒和病菌,富集很多有毒有害物质。呼吸系统是PM2.5暴露和作用的主要靶器官,呼吸系统疾病种类繁多,病因复杂,结局较难把握。已有报道,PM2.5对呼吸系统阻塞性、感染性、过敏性疾病及肿瘤等发生发展有重要影响,其机制可能与氧化应激、炎症反应、基因毒性、细胞凋亡、细胞自噬及细胞周期紊乱等相关。
The chemical composition of PM2.5 is extremely complex and it can carry some viruses and bacteria,gather many toxic and hazardous substances.The respiratory system is the main target organ of PM2.5 exposure and impact.There are many different kinds of respiratory system diseases,which have complex etiologies and unpredictable outcomes.Previous reports have shown that PM2.5 plays an important role in the occurrence and development of respiratory obstructive,infectious,allergic and neoplastic diseases;of which mechanisms may be related to oxidative stress,inflammatory reaction,genetic toxicity,cell apoptosis,cell autophagy and cell cycle disorders.
作者
易建华
吴晓芳
王丽云
雷剑
韩晶
YI Jian-hua;WU Xiao-fang;WANG Li-yun;LEI Jian;HAN Jing(School of Public Health,Xi'an Jiaotong University Health Science Center,Xi'an 710061;Women and Children's Hospital of Northwest,Xi'an 710061,China)
出处
《西安交通大学学报（医学版）》
CAS
CSCD
北大核心
2019年第1期167-172,共6页
Journal of Xi’an Jiaotong University（Medical Sciences）
基金
中国博士后面上项目(No.2018M633530)
中国科学院地球环境研究所黄土与第四纪地质国家重点实验室开放基金资助项目(No.SKLLQG1706)
陕西省重点产业创新链项目(No.2018DCXL-SF-02-03-01)~~
