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体外膈肌起搏器在机械通气患者中的应用效果 被引量:19

Efficacy of external diaphragm pacemaker applied to patients with mechanical ventilation
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摘要 目的探讨体外膈肌起搏器(EDP)在机械通气患者中的应用效果。方法将78例接受机械通气的患者随机分为EDP组38例和对照组40例。两组均给予常规治疗,EDP组同时采用EDP治疗。在入组时、治疗后第3天及第7天、撤机前采用超声评估患者右侧膈肌增厚分数(DTF);比较两组患者的机械通气及ICU入住时间、28 d撤机成功率。结果两组患者机械通气时间、ICU入住时间、28 d撤机成功率比较,差异均无统计学意义(均P> 0. 05)。两组的DTF均呈先下降后上升的趋势(P <0. 05),但撤机前EDP组的DTF大于对照组(P <0. 05)。结论 EDP能一定程度改善机械通气患者的膈肌功能,可用于机械通气患者的早期康复治疗。 Objective To investigate the efficacy of external diaphragm pacemaker( EDP) applied to the patients with mechanical ventilation( MV). Methods Seventy-eight patients receiving MV were randomly divided into EDP group( n = 38) and control group( n = 40). The conventional treatment was performed in both groups,and the EDP group was also treated with EDP. Before enrollment,on the 3 rd and 7 th day after treatment,and before liberation from MV,the right diaphragmatic thickening fraction( DTF) was assessed using ultrasound; the duration for MV,ICU stay and the success rate of MV withdrawal within 28 days were compared between the two groups.Results There were no statistically significant differences between the two groups in the duration for MV,ICU stay,or success rate of MV withdrawal within 28 days( all P > 0. 05). DTF declined at first and then rose in both groups( P < 0. 05),but before MV withdrawal,DTF of the EDP group was greater than that of the control group( P < 0. 05). Conclusion EDP can improve the diaphragmatic function of the patients with MV to a certain extent,and can be applied to early rehabilitation in the patients with MV.
作者 江意春 刘晓君 刘振密 钟樟桂 袁丰华 张华东 刘雪燕 JIANG Yi-chun;LIU Xiao-jun;LIU Zhen-mi;ZHONG Zhang-gui;YUAN Feng-hua;ZHANG Hua-dong;LIU Xue-yan(ICU,the Second Clinical Medical College of Jinan University & Shenzhen People's Hospital,Shenzhen 518020,China)
出处 《广西医学》 CAS 2018年第23期2786-2788,2791,共4页 Guangxi Medical Journal
基金 广东省深圳市卫生和计划生育委员会科研项目(SZFZ2017042)
关键词 机械通气 体外膈肌起搏器 膈肌功能 Mechanical ventilation External diaphragm pacemaker Diaphragmatic function
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