摘要
目的探讨眶上锁孔入路、超声吸引器在鞍结节脑膜瘤手术治疗中的应用效果。方法分析2014年1月至2017年1月福建医科大学附属协和医院和柳州市中医医院收治的65例鞍结节脑膜瘤的临床资料,根据手术治疗方法分为对照组与观察组。其中32例患者接受常规手术治疗为对照组,另33例患者接受眶上锁孔入路、超声吸引器治疗为观察组。比较两组患者肿瘤有效切除率、神经功能缺损程度(GCS评分)、并发症及生活质量。结果观察组患者肿瘤有效切除率(96. 67%)高于对照组(78. 13%)(P<0. 05)。两组患者神经功能缺损程度术前差异无统计学意义(P>0. 05),术后观察组神经功能缺损程度低于对照组(GCS评分15. 98±1. 23比12. 59±1. 22)(P<0. 05)。观察组患者并发症发生率(6. 06%)低于对照组(21. 88%)(P<0. 05)。两组患者术前生活质量SF-36评分差异无统计学意义(P>0. 05),术后在生理功能、生理职能、躯体疼痛、总体健康、活力、社会功能、情感职能、精神健康评分均有升高,但观察组患者术后以上各项评分均高于对照组(均P<0. 05)。结论眶上锁孔入路联合超声吸引器治疗鞍结节脑膜瘤疗效较佳,能在提高治疗效果的同时改善患者生活质量,术后并发症少,神经损伤小,值得临床推广应用。
Objective To investigate the application of supraorbital keyhole approach and ultrasonic aspirator in surgical treatment of tuberculum sellae meningiomas.Methods The clinical data of the tuberculum sellae meningiomas treated in our hospital from January2014to January2017were retrospectively analyzed.Patients were divided into two groups according to different surgical methods.Thirty-two patients in the control group received routine surgery,while33patients in the observation group underwent supraorbital keyhole approach and ultrasonic aspirator treatment.The tumor resection effect,Glasgow coma scale(GCS),complications,and quality of life scores were compared between the two groups.Results The effective rate of tumor resection in the observation group was significantly higher than that in the control group(P<0.05);The GCS score had no difference before surgery(P>0.05),which was higher in the observation group than in the control group after treatment(P<0.05).The overall incidence of complications in the observation group was significantly lower than that in the control group(P<0.05).The SF-36quality of life score of the two groups had no difference before treatment(P>0.05).After treatment,the scores of the physiological function(PF),physical role(RP),pain(P),general health(GH),vitality(VT),social function(SF),role of emotion(RE),and mental health(MH)were increased,and were higher in the observation group than those in the control group(all P<0.05).Conclusions The application of the supraorbital keyhole approach and ultrasonic aspirator can improve the quality of life and reduce the nerve damage with fewer complications in surgical treatment of tuberculum sellae meningiomas,which is recommended.
作者
蓝天才
陈春美
石松生
LAN Tiancai;CHEN Chunmei;SHI Songsheng(Department of Neurosurgery,Liuzhou Traditional Chinese Medicine Hospital,Liuzhou 535001,China;Department of Neurosurgery,Union Hospital of Fujian Medical University,Fuzhou 350000,China)
出处
《中国肿瘤外科杂志》
CAS
2018年第6期376-378,384,共4页
Chinese Journal of Surgical Oncology
关键词
眶上锁孔入路
超声吸引器
鞍结节脑膜瘤
手术
有效切除率
生活质量
Supraorbital keyhole approach
Ultrasonic aspirator
Tuberculum sellae meningiomas
Operation
Resection rate
Living quatity
