摘要
目的探讨米力农雾化吸入治疗7 d对心力衰竭患儿心功能的影响。方法选取2015年6月～2017年6月于北京儿童医院心内科就诊的50例心力衰竭患儿为研究对象,在常规抗心力衰竭治疗基础上给予米力农雾化吸入治疗。记录米力农雾化吸入治疗前后患儿心率、呼吸、血压、脑钠肽(BNP)、心功能指标变化及治疗期间不良反应发生情况。结果米力农雾化吸入治疗7 d后显效率为48.0%,有效率为42.0%,总有效率为90.0%。与米力农雾化吸入前相比,雾化吸入后左室射血分数(t=3.718,P<0.05)、BNP比较差异均具有统计学意义(P<0.05),心率、血压比较差异均无统计学意义(P>0.05)。结论短期雾化吸入米力农能够改善心功能,在儿童心力衰竭的治疗上是一种安全有效、依从性高、可推广的方法。
Objective To investigate the effect of milrinone inhalation on heart function in children with heart failure for7days.Methods A total of50children with heart failure who were admitted to the Department of Cardiology of Beijing Children's Hospital from June2015to June2017were enrolled.The patients were treated with conventional anti-heart failure treatment.The heart rate,respiration,blood pressure,brain natriuretic peptide(BNP),cardiac function index and adverse reactions during treatment were recorded before and after treatment with milrinone.Results After7days of milrinone inhalation treatment,the effective rate was48.0%,the effective rate was42.0%,and the total effective rate was90.0%.Compared with milrinone before nebulization,the left ventricular ejection fraction after nebulization(t=3.718,P<0.05),the difference of BNP was statistically significant(P<0.05).There was no significant difference in heart rate and blood pressure(P>0.05).Conclusion Short term nebulization of milrinone treatment can improve the heart function in children with heart failure.It is a safe and effective,with high compliance and promotion method.
作者
于霞
袁越
孙成磊
刘新灵
程国良
徐健
徐爱峰
Yu Xia;Yuan Yue;Sun Chenglei;Liu Xinling;Cheng Guoliang;Xu Jian;Xu Aifeng(Department of Cardiology,Beijing Children's Hospital affiliated toCapital Medical University,Beijing 100045,China)
出处
《中国循证心血管医学杂志》
2018年第11期1348-1350,共3页
Chinese Journal of Evidence-Based Cardiovascular Medicine
基金
北京市卫生与健康科技成果和适宜技术推广项目(TG-2017-26)
关键词
米力农
雾化吸入
静脉输注
心力衰竭
儿童
Milrinone
Nebulization therapy
Intravenous infusion
Heart failure
Children
