摘要
为研究牡丹籽油对小鼠免疫功能的影响,以21日龄ICR清洁级雄性小鼠为研究对象,连续灌胃不同剂量的牡丹籽油及牡丹籽油复合物20 d,测定并分析血清NO、NOS,脾脏IL-2、IL-6、TNF-α和肠粘膜组织s Ig A的变化。结果表明:与对照相比,牡丹籽油能显著提高小鼠血清NO水平和脾脏IL-2水平,显著降低脾脏TNF-α水平,并能显著提高肠道粘膜s Ig A水平,说明牡丹籽油能提高动物机体的免疫机能。
In order to study the effects of peony seed oil on immune function in mice,21-day-old ICR male mice were given different doses of peony seed oil and peony seed oil complex for 20 days,and the changes of NO,NOS in serum,IL-2,IL-6,TNF-a in spleen and sIgA in intestinal mucosa tissue were determined and analyzed.The results showed that compared with the control group,peony seed oil could significantly increase the level of NO in serum and IL-2 in spleen of mice,significantly reduce TNF-αlevel in spleen,and significantly increase sIgA level in intestinal mucosa.It showed that peony seed oil could improve the immune function of animals.
作者
孙燕
李成忠
左伟勇
SUN Yan;LI Cheng-zhong;ZUO Wei-yong(Jiangsu Provincial Key Laboratory of Veterinary Bio-pharmaceutical High Tech Research,Taizhou 225300,China)
出处
《上海农业学报》
CSCD
2018年第6期65-68,共4页
Acta Agriculturae Shanghai
基金
江苏省"青蓝工程"青年骨干教师培养对象资助项目[苏教师(2016)15号]
江苏省林业三新工程项目[LYSX(2015)03]
江苏农牧科技职业学院立项课题(NSF201512)
