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右美托咪定不同给药方式麻醉在腹腔镜手术治疗子宫肌瘤中的麻醉效果研究 被引量:44

Study on anesthesia effect of different administration methods of dexmedetomidine in gynecological laparoscopic surgery
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摘要 目的:分析并探讨右美托咪定不同的麻醉给药方式在妇科腹腔镜手术中的临床效果,从而为临床上选择合适的麻醉方式提供依据。方法:选取2014年12月至2016年12月在医院选择腹腔镜手术治疗的妇科患者120例,随机分为观察组与对照组,每组60例。观察组单次注射右美托咪定,对照组持续注射右美托咪定。观察两组麻醉效果。结果:两组患者心率、血压无显著差异(P>0.05)。观察组拔管时间为(16.14±4.86)min,苏醒时间为(3.67±1.43)h,OAA/S评分为(4.75±1.15);对照组拔管时间为(22.49±5.86)min,苏醒时间为(4.86±2.49)h,OAA/S评分为(3.25±0.88),观察组拔管时间及苏醒时间以及OAA/S评分优于对照组(P<0.05)。观察组不良反应发生率为18.33%,对照组为35.00%,观察组不良反应发生率低于对照组(P<0.05)。结论:单次静脉注射右美托咪定应用于妇科腹腔镜手术中,可以有效的提高麻醉效果,有助于维持血流动力学稳定。 Objectives:To analyze and explore the clinical effect of different administration methods of dexmedetomidine in gynecological laparoscopic surgery,to select suitable anesthesia methods for clinical practice.Methods:120 gynecological patients in our hospital from December 2014 to December 2016 were selected and randomly divided into observation group and control group(n=60).The observation group received a single injection of dexmedetomidine,and the control group received continuous injection of dexmedetomidine.Anesthesia effect of the two groups were observed.Results:There was no significant difference in heart rate and blood pressure between the two groups(P>0.05).In observation group,the duration of extubation was(16.14±4.86)min,the recovery time was(3.67±1.43)h,and the OAA/S score was(4.75±1.15).In control group,the duration of extubation was(22.49±5.86)min,the recovery time was(4.86±2.49)h,and the OAA/S score was(3.25±0.88).The extubation time,recovery time and OAA/S score of observation group were better than those of control group(P<0.05).The incidence of adverse reactions was 18.33%in observation group and 35.00%in control group,with significant difference(P<0.05).Conclusion:Single intravenous administration of dexmedetomidine in gynecologic laparoscopic surgery can effectively improve the effect of anesthesia and help maintain hemodynamic stability
作者 王跃斌 孙广运 何常佑 杜秋 陈家莲 高竟 WANG Yuebin;SUN Guangyun;HE Changyou;DU Qiu;CHEN Jialian;GAO Jing(Department of Anesthesiology,Yibin Second People's Hospital,Yibin 644000,Sichuan,China;Department of Obstetrics and Gynecology,Yibin Second People's Hospital,Yibin 644000,Sichuan,China;Department of Obstetrics and Gynecology,Dujiangyan People's Hospital,Chengdu 611830,Sichuan,China)
出处 《中国性科学》 2018年第3期34-36,共3页 Chinese Journal of Human Sexuality
基金 四川省科技支撑计划项目(10ZC1820)
关键词 麻醉 右美托咪定 腹腔镜 给药方式 Anesthesia Dexmedetomidine Laparoscopy Administration method
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  • 1盛恒炜,徐世元,何援丽.术中监测脑氧代谢及血流灌注对预防术后神经功能损伤的作用[J].中国临床康复,2004,8(19):3784-3785. 被引量:9
  • 2姜雨鸽,徐龙河,张宏.异丙酚对大鼠肺动脉平滑肌细胞钾通道电流的影响[J].中国临床药理学与治疗学,2007,12(7):756-759. 被引量:1
  • 3Mantz J, Josserand J, Hamada S. Dexmedetomidine : new insights [ J. Eur J Anaesthesiol, 2011,28 ( 1 ) :3 - 6.
  • 4Afonso J, Reis F. Dexmedetomidine: current role in anesthesiaand intensive care [ J ]. Rev Bras Anestesiol, 2012,62 ( 1 ) : 118 - 33.
  • 5Dere K, Sucullu I, Budak E T, et al. A comparison of dexme- detomidine versus midazolam for sedation, pain and hemodynamic control, during colonoscopy under conscious sedation [ J ]. Eur J Anaesthesiol, 2010,27 (7) :648 - 52.
  • 6Wei S, Tian J, Song X, et al. Association of perioperative fluid balance and adverse surgical outcomes in esophageal cancer and esophagogastric junction cancer [ J ]. Ann Thorac Surg, 2008,86 ( 1 ) :266 - 72.
  • 7Lawrence C J, Prinzen F W, de Lange S. The effect of dexmedeto- midine on nutrient organ blood flow J ]. Anesth Analg, 1996,83 (6) :1160 -5.
  • 8Tsai C J, Chu K S, Chen T I, et al. A comparison of the effec- tiveness of dexmedetomidine versus propofol target-controlled infu- sion for sedation during fibreoptie nasotracheal intubation[ J]. An- aesthesia, 2010,65 ( 3 ) :254 - 9.
  • 9Aksu R, Kumandas S, Akin A, et al. The comparison of the effects of dcxmedetomidine and midazolam sedation on eleetroen- cephalography in pediatric patients with febrile convulsion [ J . Paediatr Anaesth, 2011,21 (4) :373 - 8.
  • 10Kabukcu HK,Sahin N,Temel Y,et al. Hemodynamics in cor- onary artery bypass surgery: effects of intraoperative dexme- detomidine administration[J]. Anaesthesist, 2011,60 : 427-431.

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