摘要
目的探究哌拉西林他唑巴坦联合阿奇霉素对大叶性肺炎患儿血清C反应蛋白(CRP)、红细胞沉降率(ESR)水平变化及康复进程的影响。方法选取2015年3月~2016年12月本院大叶性肺炎患儿84例,采用随机数表法分组,各42例。对照组予以头孢吡肟治疗,观察组予以哌拉西林他唑巴坦+阿奇霉素治疗。对比两组临床疗效,测定对比治疗前后两组血清CRP、ESR水平,对比两组咳嗽缓解、发热消失、肺部阴影完全吸收时间。结果观察组治疗总有效率92.86%(39/42)高于对照组76.19%(32/42),差异有统计学意义(P<0.05);治疗后观察组血清CRP、ESR水平低于对照组,差异有统计学意义(P<0.05);观察组咳嗽停止、发热消失、肺部阴影完全吸收时间均短于对照组,差异有统计学意义(P<0.05)。结论哌拉西林他唑巴坦联合阿奇霉素治疗大叶性肺炎患儿疗效显著,可减轻患儿炎症反应,缩短康复进程。
Objective To investigate the effect of piperacillin tazobactam combined with azithromycin on serum C-reactive protein(CRP),erythrocyte sedimentation rate(ESR)and rehabilitation in children with lobar pneumonia.Methods From March2015to December2016,84children with lobar pneumonia were selected and randomly divided into control group and observation group,each group42cases.The control group was treated with cefepime,and the observation group was treated with piperacillin tazobactam+azithromycin.Clinical efficacy were compared between the two groups,and serum CRP and ESR levels before and after treatment were measured and compared,and compared inaddition,compare condition of the cough retiet,fever disappeared,the lungs completely absorb.Results The total effective rate in the observation group92.86%(39/42)was higher than that of the control group76.19%(32/42),the difference was statistically significant(P<0.05);The levels of serum CRP and ESR in the observation group were significantly lower than those in the control group after treatment(P<0.05);The cough stopped,the fever disappeared and the complete absorption time of the lungs in the observation group were shorter than the control group,the difference was statistically significant(P<0.05).Conclusion Piperacillin tazobactam combined with azithromycin in the treatment of lobar pneumonia in children has a significant effect,which can reduce the inflammatory response in children,shorten the recovery process.
作者
杨阳
YANG Yang(Shangcai Covnty People's Hospital,Zhumadian, Henan,463800,China)
出处
《临床研究》
2018年第4期65-67,共3页
Clinical Research
