摘要
目的:观察三乙醇胺混合凡士林乳膏用于腋臭微创术后患者创面的临床疗效。方法:对笔者医院接受微创腋臭手术治疗且符合研究要求的患者进行临床观察,根据治疗方法将患者分为三组:三乙醇胺治疗组(37例)、凡士林治疗组(40例)、联合治疗组(40例)。比较三组患者治疗前后经表皮水分丢失情况、皮肤瘢痕(SBSES量表评分)、表皮厚度及相关生化指标含量、预后效果的差异。结果:治疗前三组患者基本资料、经表皮水分丢失情况的差异均无统计学意义(均P>0.05);治疗后三组患者经表皮水分丢失情况、皮肤瘢痕(SBSES量表评分)、愈合时间和并发症的差异均具有统计学意义(均P<0.05),具体表现在三乙醇胺治疗组和联合治疗组、凡士林治疗组和联合治疗组之间有显著性差异(均P<0.05);治疗前后比较,三乙醇胺治疗组、凡士林治疗组患者经表皮水分丢失情况差异无统计学意义(均P>0.05),凡士林治疗组和联合治疗组患者的差异明显(P<0.05);三组患者治疗后表皮厚度、VEGF m RNA、IL-36αm RNA、IL-36α蛋白等生化指标含量的差异均有统计学意义(均P<0.05)。结论:三乙醇胺混合凡士林乳膏用于腋臭患者微创手术后,能明显加快患者皮肤愈合速度和增强皮表的屏障作用,同时有助于减少转归过程中并发症的发生。
Objective To understand the clinical efficacy of triethanolamine mixed vaseline cream for minimally invasive surgery for patients with armpit odor,and to provide theoretical experience for the clinical promotion of the treatment method.Methods In February2011-December2015,for the treatment of bromhidrosis minimally invasive surgery in our hospital,to meet the requirements of the patients in the control study,according to its treatment is divided into three groups:the treatment group(37cases),triethanolamine vaseline treatment group(40cases),triethanolamine joint vaseline treatment group(40cases).Comparison of the water loss,skin scar(SBSES scale score),skin histopathological correlation index and prognosis of the three groups were compared.Results There was no statistically significant difference between the three groups of patients in the first three groups(P>0.05).Three groups of patients after treatment by the skin moisture loss situation,the skin scar(SBSES rating scale),the healing time and complications of the differences were statistically significant(P<0.05),the specific performance in the presence of the treatment group and combination group,vaseline,the treatment group and the difference between combined treatment group(P<0.05),Triethanolamine compared before and after treatment,the treatment group,vaseline treatment group patients with the skin moisture loss condition of no statistical significance(P>0.05),the group treated with vaseline and combined treatment group of patients with significant difference(P<0.05).The differences in the levels of epidermal thickness,VEGF mRNA,il-36alpha mRNA,il-36alpha protein and other biochemical indexes in the three groups were statistically significant(P<0.05).Conclusion Triethanolamine joint vaseline ointment for osmidrosis patients after minimally invasive surgery,can significantly speed up the patients skin healing and skin barrier function,also help reduce the outcome in the process of the occurrence of complications.
作者
向光俊
杨洪政
XIANG Guang-jun;YANG Hong-zheng(Department of Burns and Plastic Surgery,Affiliated Renhe Hospital of China Three Gorges University,Yichang 443000, Hubei,China)
出处
《中国美容医学》
CAS
2018年第2期72-75,共4页
Chinese Journal of Aesthetic Medicine
关键词
三乙醇胺
凡士林
腋臭
微创手术
triethanolamine
petroleum jelly
bromhidrosis
minimally invasive surgery
