摘要
目的分析维甲酸联合NB-UVB治疗皮肤淀粉样变的临床效果。方法将2012年5月-2017年3月到我院接受治疗的88例皮肤淀粉样变患者选取为研究对象,根据治疗方法不同,将其随机分为对照组和联合组两组,每组均为44例,对照组患者采用维A酸软膏进行治疗,联合组患者则采用维甲酸联合NB-UVB治疗,之后再对比两组患者的临床治疗效果。结果对照组患者的治疗总有效率与联合组相比存在明显差异,有统计学意义(P<0.05);且对照组患者的不良反应发生率明显高于联合组,差异具备统计学意义(P<0.05)。结论对于皮肤淀粉样变患者而言,采用维甲酸联合NB-UVB治疗,可以使患者的治疗效果实现显著的提升,有效的降低不良反应发生率,有助于促进患者早日康复,其治疗效果远远优于卤米松软膏联合NB-UVB的治疗效果,是一种较为理想的皮肤淀粉样变疾病治疗办法,值得在临床中大力推广采用。
Objective To analyze the clinical efficacy of retinoic acid combined with NB-UVB in the treatment of skin amyloidosis.Methods May2012to March2017in our hospital treated88cases of cutaneous amyloidosis were selected as the research object,according to the different treatment methods,they were randomly divided into control group and combined group two groups,each group had44cases,the control group was treated with A retinoic acid ointment for treatment,combined group treated with retinoic acid combined with NB-UVB treatment,then compared the clinical treatment effect of the two groups of patients.Results The control group the total efficiency and combined group differences,with statistical significance(P<0.05);and the control group of patients with adverse reaction rate was significantly higher than that of the combined group,the difference has statistical significance(P<0.05).Conclusion For skin amyloidosis patients,by retinoic acid combined with NB-UVB treatment,can make patients achieve significantly improved,effectively reduce the incidence of adverse reactions,help to promote the recovery of patients,the treatment effect is better than single vitamin A,is an ideal skin amyloid variable disease treatment,it is worth popularizing in clinical use.
作者
孙比男
郦彬
邹瑞芳
SUN Bi-nan;LI Bin;ZOU Rui-fang(Fuzhou Jinan District Hospital, Fujian Province, 350000, China)
出处
《中国医疗美容》
2017年第12期49-52,共4页
China Medical Cosmetology
