摘要
目的:探讨术中自体血液回输对颅脑手术治疗患者免疫功能的影响。方法:将颅脑手术治疗且术中有输血的110例患者随机分为2组,每组55例,观察组术中采用自体血液回输治疗,而对照组术中采用异体输血治疗。结果:(1)手术前,两组患者血常规、凝血指标、免疫功能差异无统计学意义(P>0.05)。术后第8天,观察组RBC、Hb、IL-6、IFN-γ高于对照组(P<0.05)。(2)观察组术后感染率低于对照组,差异有统计学意义(χ~2=4.9495,P=0.0265)。结论:颅脑手术治疗患者术中采用自体血液回输的疗效良好,具有RBC及Hb维持效果好、免疫功能影响小、术后感染率低等优点。
Objective:To observe the effects of intraoperative autologous blood transfusion on immune function in patients undergoing craniocerebral operation.Methods:110patients undergoing craniocerebral surgery were randomLy divided into observational group(received autologous blood transfusion)and control group(received allogeneic blood transfusion)(n=55for each).Results:①Patients in the two groups had no significant difference concerning the preoperative routine blood studies,coagulation indicator and immunologic function(P>0.05),yet patients in the observational group had significantly higher red blood cell(RBC),hemoglobin(Hb),IL6and IFNγlevels than those in the control group at day8following operation(P<0.05);②Patients in the observational group had lower infection rate than those in the control group(χ2=4.9495,P=0.0265).Conclusion:Intraoperative autologous blood transfusion can be effective for patients undergoing craniocerebral surgery,and have more advantages,including better maintenance of RBC and Hb as well as less effect on the immunity and lower postoperative infection.
作者
钟青
谭军
欧阳玲
ZHONG Qing;TAN Jun;OUYANG Ling(Department of Blood Transfusion,Songgang People′s Hospital of Baoan District,Shenzhen 518105,China)
出处
《皖南医学院学报》
CAS
2017年第6期579-581,共3页
Journal of Wannan Medical College
关键词
自体血液回输
异体输血
颅脑手术
免疫功能
autologous blood transfusion
allogeneic blood transfusion
craniocerebral operation
immune function
