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CD_(44V6)分子在人胃癌中的表达及其意义

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摘要 肿瘤细胞表面的粘附分子在恶性肿瘤浸润转移过程中起着重要作用[1].CD44是粘附分子家族成员之一,可存在于多种恶性肿瘤中,其多种拼接变异体与肿瘤转移、复发有明显关系[2].研究表明,CD44拼接变异体(CD44 splice variants, CD44v)的表达,特别是CD44V6的表达与胃癌浸润、转移、复发关系密切[3].我们采用流式细胞术检测CD44V6在胃癌中的表达特征及其与胃癌临床病理特征的关系,探讨CD44V6表达在判断胃癌浸润、转移及预后中的意义.
出处 《中华消化内镜杂志》 2002年第5期292-294,共3页 Chinese Journal of Digestive Endoscopy
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