摘要
目的 探讨脐血清瘦素水平与新生儿出生体重、体重指数 (bodymassindex ,BMI)、性别、胎盘重量以及分娩方式的关系。方法 采用放射免疫法检测了 12 0例新生儿脐静脉血清瘦素水平 ,并分析其与出生体重、BMI、性别、胎盘重量以及分娩方式的相关性。结果 ① 60例女婴脐血清瘦素水平为 (10 76± 2 5 8) μg/L ,60例男婴脐血清瘦素水平为 (9 73± 2 40 ) μg/L ,其差异无显著性 (P >0 0 5 ) ;64例顺产组脐血清瘦素水平为 (10 94± 2 3 5 ) μg/L ,5 6例选择性剖宫产组脐血清瘦素水平为 (9 80± 2 0 9) μg/L ,其差异同样无显著性 (P >0 0 5 ) ;②脐血清瘦素水平与其体重、BMI的相关系数在女婴组分别为 :0 86、0 66(P <0 0 1) ,男婴组分别为 0 49、0 3 5 (P <0 0 1) ;脐血清瘦素水平与胎盘重量的相关系数在女婴组为 0 0 5 (P >0 0 5 ) ,男婴组为 0 16(P >0 0 5 )。
Objective To measure the leptin concentration in cord blood and to study its relationship with neonatal body weight , body mass index, gender, placental weight and mode of delivery.Methods Levels of umbilical venous leptin were measured in 120 newborns by Immuno-radioassay method. Serum leptin concentration was correlated with body weight, body mass index, gender, placental weight and mode of delivery.Results ① Serum leptin levels of 60 female neonates [(10 76±2 58)μg/L] were not significantly different from those of 60 male neonates [(9 73±2 40)μg/L], Serum leptin levels of 64 neonates in the vaginal delivery group [(10 94±2 35)μg/L] were not significantly different from those of 56 neonates in the elective cesarean group [(9 80±2 09)μg/L], ②Leptin concentrations of female and male newborns were positively correlated with their body mass and body weight index, but not significantly correlated with placental weight. Conclusion The cord serum leptin levels can be used as a reliable parameter for evaluating intrauterine fetal growth .
出处
《广东医学》
CAS
CSCD
2002年第10期1032-1033,共2页
Guangdong Medical Journal
