摘要
18F-FDG显像可以提供肿瘤细胞生物特性信息,且大多数肿瘤具有靶/非靶高比率的特性,目前已有效地应用于全身各种肿瘤。但是,除肿瘤外,正常组织及一些良性病变也可摄取18F-FDG,这些非肿瘤摄取常可造成假阳性或者掩盖恶性肿瘤灶。通过阐述各种非肿瘤性摄取,包括生理性、良性、炎症性摄取的特点以及鉴别点,图像融合、双时相显像应用到非肿瘤性摄取的鉴别,认为同机图像融合是鉴别肿瘤性摄取与生理性摄取首选方法。
F-FDG imaging can provide information about the biologic characteristics o f malignant cells,and has high target-to-nontarget ratios in most common n eoplasms,recently has been successfully used in various neoplasms throughout the body.However 18 F-FDG is a non specific tracer,and it has been found to accumulate at site s of normal tissue and some benign pathologic.This uptake of nonmalignant tiss ue may be misinterpreted as a false positive result or mask a nearby malignant lesion.We describe various nonmalignant uptake's characteristic and differenti al including physiologic,benign,infection and inflammation,image fusion,dual time point imaging be applied to distinguish nonmalignant accumulations.Con sider the combined imaging fusion is the first optimal modality in distinguish m alignant accumulations from physiologic.
出处
《国外医学（放射医学核医学分册）》
2002年第5期205-209,共5页
Foreign Medical Sciences(Section of Radiation Medicine and Nuclear Medicine)
关键词
^18F-氟代脱氧葡萄糖
生理性摄取
肿瘤
鉴别诊断
F-fluoro-2-deoxy-D-glucose
physiological accumulations
benign pathol ogic
neoplasms
differential
