摘要
本文在分析垂体腺瘤的临床表现、影像学特征、治疗及病理特点的同时,利用立体定量测量、电镜观察和流式细胞术 DNA 测量、对102例(复发者54例,未复发者48例)经手术治疗的垂体腺瘤作了回顾性分析。通过比较,对肿瘤大小、生长方式、分类、细胞学特征及术后放疗等因素与垂体腺瘤术后复发的关系进行了研究,并对术后复发的预测作了初步探讨。
The postoperative recurrence of pituitary adenomasis an important problem for neurosugeon.In ourhospital,the recurrent rate is 13.33%.The characte-ristics of 102 cases of pituitary adenomas concer-ning clinic,radiological investigation,the treatmentand pathological examination were analysed.Inthis study,flow cytometry,cell morphometry andelectron microscope were used,By comparing 54recurrent cases with 48 unrecrrent cases,thedangerous factors for the recurrence of pituitaryadenoma were as follow;(1)macroadenomas;(2)invasive tumors;(3)incomplete removal of tumor;(4)poor differentiation and active proliferation oftumorous cells;(5)feedback pituitary adenomascaused by long time hypofunction of target organ;(6)higher DNA index and aneuploid adenoma;(7)improper postoperative radiotherapy.If everyfactor is known,the danger of postoperativerecurrence of pituitary adenoma will be predicted.
出处
《中华神经外科杂志》
CSCD
北大核心
1991年第3期171-175,F003,共6页
Chinese Journal of Neurosurgery