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山莨菪碱减轻甘露醇对外周静脉损伤的研究 被引量:101

Experimental study of using anisodamin to lighten the lesion of mannital to the external vein
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摘要 目的 :探讨局部外用扩血管药对外周静脉的防护。方法 :动物实验 :采用不同药物的溶液 ,涂抹兔耳缘静脉的局部皮肤 ,5min后分别用 35℃甘露醇静点。以穿刺点及近心端距穿刺点 1cm处为中心 ,活体时各切下面积 1.0cm2 的耳廓组织 ,放入 10 %福尔马林溶液内固定 2 4h ,做病理检查。临床实验 :5 0例患者采用 2 %山莨菪碱涂抹局部静脉皮肤 ,5min后静点 35℃甘露醇 ,并与对照组 5 0例静滴常温甘露醇及 5 0例静滴 35℃甘露醇的患者进行了对照比较。结论 :应用不同的扩血管药后 ,甘露醇对血管的损伤减轻 。 Objective: To research the preservation of external vein with local external remedy to dilate blood vein.Method: Animal Experiment:To apply venous local skin of the rabbit ear with different medicine liquids. Drip 35℃mannitol in the vein in 5 minutes. The center was 1cm from the puncture point to, the apex of heart as well as the point. Cut off the living auricle tissues, each area was 1.0cm 2, and fixed them in 10% formalin for 24 hours for pathological examination. Clinical Experiment:50 cases were adoptted to apply local skin with 2%Anisodamin and drip 35℃ mannitol in the vein in 5 minutes compared with another 50 cases,who were dripped in vein at common temperature. Result: Different medicine of dilating blood vessel to drip mannitol make different lesion of vein(blood vessel). Using Anisodamin on local skin, the lesion of vein was the lightest. It was the effective measure to prevent phlebitis.
出处 《中华护理杂志》 CSCD 北大核心 2002年第10期729-732,共4页 Chinese Journal of Nursing
基金 中国人民解放军第 2 5 1医院院内科研课题
关键词 山莨菪碱 静脉炎 预防 防护 外周静脉损伤 甘露醇 Anisodamine Mannitol Veins Research
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