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异种(猪)脱细胞真皮基质与头皮薄皮片复合移植 被引量:11

Application of meshed acellular dermis xenograft(pigskin)with scalp thin skin autograft in 15 patients
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摘要 目的 探索异种 (猪 )脱细胞真皮基质与头皮薄皮片复合移植在整形修复方面应用的可行性。方法 将制备好的异种 (猪 )脱细胞真皮基质移植于烧伤切痂、肉芽及瘢痕切除的创面上 ,4~ 5d后再移植自体头皮薄皮片 ,并观察其成活率 ,以及创面修复后的质量。结果  15例 2 5个创面 ,脱细胞真皮基质的成活率 (96 4 0± 2 6 0 ) % ,头皮薄皮片的成活率 (97 4 4± 3 5 0 ) % ,创面愈合后皮肤的颜色与正常皮肤近似 ,外观平整 ,弹性良好 ,无明显的瘢痕增生 ,相当或接近于自体大张中厚皮片移植的修复效果。结论 异种 (猪 )脱细胞真皮基质与自体头皮薄皮片复合移植 ,成活率高 ,整复效果较为满意 ,头皮供区可反复供皮而不留瘢痕及影响头发生长 ,是修复深度烧伤及瘢痕切除后创面的可行手术方法。 Objective\ To present the clinical application of the meshed acellular dermis xenograft with scalp thin split thickness skin autograft. Methods\ The meshed acellular dermis xenograft (pigskin) was placed on the granulation or defects after scar resection. Four or five days afterwards, scalp thin split thickness skin was transplanted. A total of 15 patients with 25 wounds were treated using this technique. The survival rates and quality of the grafts were observed. Results\ The survival rate of the meshed acellular dermis xenograft was (96 40 ± 2.60)% and the scalp thin split thickness skin autograft was (97.44 ± 3.50)%. All grafts showed normal skin alike color and elastic and smooth texture. Conclusion\ The combined use of meshed acellular dermis xenograft and scalp skin autograft demonstrated an ideal way for the repair of full thickness skin burn or defects from scar resection. The scalp can provide thin skin graft repeatedly without influence of the hair.\;
出处 《中华整形外科杂志》 CAS CSCD 北大核心 2002年第5期273-275,T002,共4页 Chinese Journal of Plastic Surgery
关键词 脱细胞真皮基质 头皮薄皮片 烧伤 瘢痕 异种皮 Acellular dermis matrix Split thickness thin skin Burn Scar
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  • 1冯世杰,烧伤,1996年,120页
  • 2杨之骏,烧伤治疗(第2版),1985年,70页
  • 3李迟,中华整形烧伤外科杂志,1992年,8卷,241页
  • 4陈璧,中华整形烧伤外科杂志,1990年,7卷,29页

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