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氧自由基与高血压关系研究进展 被引量：5

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摘要 越来越多的证据表明 ,氧自由基参与高血压的发生、发展及并发症的形成过程。本文就氧自由基的来源及其对心血管系统的作用 ,包括内皮细胞损伤、血管平滑肌细胞增殖、血管重构等进行论述 ,以探讨其致高血压发病的机制。
作者 隋辉
机构地区 中国医学科学院中国协和医科大学阜外心血管病医院心血管病研究所
出处 《高血压杂志》 CSCD 2002年第5期414-417,共4页 Chinese Journal of Hypertension
关键词 研究进展 氧自由基 高血压 抗氧化 内皮细胞
分类号 R544.1 [医药卫生—心血管疾病]
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参考文献27

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同被引文献63

  • 1李卫萍,孙明,周宏研,顾复生,贾三庆.阿托伐他汀对自发性高血压大鼠主动脉活性氧、AT_1受体和p22phox表达的影响[J].临床心血管病杂志,2005,21(2):104-107. 被引量：5
  • 2葛长江,胡申江.阿托伐他汀影响自发性高血压大鼠血压的机制探讨[J].中国病理生理杂志,2005,21(12):2324-2327. 被引量：15
  • 3葛长江,胡申江,吕树铮,陈韵岱,武垚森.阿托伐他汀对动脉内膜损伤后血管平滑肌细胞离子泵活性和内膜增殖的影响[J].临床心血管病杂志,2006,22(4):206-208. 被引量：5
  • 4Touyz RM.Reactive oxygen species in vascular biology:role in arterial hypertension[J].Expert Rev Cardiovasc Ther,2003(1):91-106.
  • 5Berry C,Brosnan MJ,Fennell J,et al.Oxidative stress and vascular damage in hypertension[J].Curr Opin Nephrol Hypertens,2001,10(2):247-255.
  • 6Channon KM,Guzik TJ.Mechanisms of superoxide production in human blood vessels:relationship to endothelial dysfunction,clinical and genetic riscfactors[J].J Physiol Pharmacol,2002,53(4 pt 1):515-524.
  • 7Majid DS,Nishyama A.Nitric oxide blockade enhances renal responses to superoxide dismutase inhibition in dogs[J].Hypertension,2002,39(2):293-297.
  • 8Zalba G,San Jose G,Moreno MU,et al.Oxidative stress in arterrial hypertension role of NADPH oxidase[J].Hypertension,2001,38(6):1395-1399.
  • 9Yan HM,Zhao J,Ma DZ,et al.The effect of pitavastatin calcium on endothelial dysfunction induced by hypercholesterolemia[J].Expert Opin Pharmacother,2011,12(10):1463-1471.
  • 10Wu R,Lamontagne D,de Champlain J.Antioxidative properties of acetylsalicylic Acid on vascular tissues from normotensive and spontaneousely hypertension rats[J].Circulation,2002,105(3):387-392.

引证文献5

二级引证文献20

高血压杂志
2002年 第5期

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