摘要
端粒和端粒酶是现代生物学研究的热点,端粒的缺失与细胞的衰老,端粒酶的活性与细胞的老化及癌化均有密切的关系。文章综述了端粒和端粒酶的结构和功能,及其与细胞衰老的关系,并在此基础之上展望了端粒酶在抗衰老、抑制肿瘤等方面的应用。
Telomeres and telomerase are in the spotlight of modern biological study.There are causal relationship be-tween telomere loss and replicative senescence,and telomerase activation and cellular senescence and immortaliza-tion.The formation and function of telomeres and telomerase and the close relationship between aging and them are reviewed,on which telomerase's application in aging control and cancer treatment is introduced.
出处
《生物技术通讯》
CAS
2002年第5期371-373,共3页
Letters in Biotechnology
关键词
端粒
端粒酶
细胞衰老
癌化
telomeres
telomerase
cellular senescence
cancer
