摘要
本文研究结果表明,应用超微结构形态测量其微绒毛、桥粒有助于胸膜恶性间皮瘤和转移性肺腺癌的鉴别。16例胸膜恶性间皮瘤平均微绒毛长宽比值(L/W)为11.76。相反,10例转移性肺腺癌平均微绒毛L/W为5.22,两者之间具有显著差异(P<0.001)。本文测量了16例恶性间皮瘤和10例转移性肺腺癌的桥粒长度,两组平均桥粒长度差异不十分显著,但是,所有16恶性间皮瘤的桥粒长度均有大于1.5μm,相反,10例转移性肺腺癌无1例桥粒长度超过1.5μm,表明恶性间皮瘤具有长的桥粒,而转移性肺腺癌则缺乏长的桥粒。
Our observations proved that ultrastructural morphometric examination of microvilli and desmosomes may help to distinguish pleural malignant mesothelioma from metastatic adenocarcinoma of lung. In 16 cases of pleural malignant mesothliona the mean ratio of leng to width (L/W) of microvilli was 11.76, whereas in 10 cases of metastatic adenocarcinoma of lung it was 5.22. The difference between them was highly significant statistically (P<0.001). The lengths of desmosomes from 16 cases of malignant mesothelioma and from 10 cases of metastatic adenocarcinoma of lung were also measured. The mean length of desmosomes was not significantly different between them. However, the length of desmosomes in all cases of malignant mesothelioma was greater than 1.5um, whereas in none of 10 cases of metastatic adenocarcin oma it was more than 1.5um. The results suggest that malignant mesothelioma have longer desmosomes while matastatic adenocarcinomas have not ones of such length.
出处
《军医进修学院学报》
CAS
1991年第3期226-228,共3页
Academic Journal of Pla Postgraduate Medical School
关键词
间皮瘤
腺癌
肺肿瘤
微绒毛
桥粒
超微结构
Mesotheioma Adenocarcinoma Lung Microvilli Desmosomes Ultrastructural
