摘要
对黑龙江省林区1322人进行调查发现LD43例,其中εCM23例,面瘫7例,脑膜脑炎3例及关节炎10例。用ELISA测定血清抗BB抗体,健康人及对照组无1例阳性;在LD组,IgM或IgG或两者阳性率在εCM、神经及关节病变组分别为95.6％、90％及100％。提示被调查地区是LD的自然疫源地及用ELISA测定抗BB抗体对诊断LD有高度特异性及敏感性。
Fourty-three of 1322 individuals studied at the forest area in Hei Longjiang province were confirmed as Lyme disease (LD). Of these 43 cases, there were erythema chronicum migrans(ECM) in 23, facial palsy in 7, meningoencephalitis in 3, and arthritis in 10. Serum anti-B. burgdorferi antibody (BB Ab) was detected by ELISA. Three SD above the mean value in 124 healthy controls, 57mg/L for IgM Ab and 60mg/L for IgG Ab were set as the normal upper limits. In 124 healthy controls and in 54 patients not related to LD, none of the individual levels of both IgM and IgG anti-BB Ab were beyond the normal limite. In contrast, the levels of serum IgM or IgG or both were above normal in 95.6% (22/23) with ECM, 90% (9/10) with neurological disorders, and 100% (10/10) with arthritis. The results suggested that LD has been found in the area studied and that the anti-BB Ab test by ELISA was a highly specific and sensitive tool for diagnosing LD.
出处
《军医进修学院学报》
CAS
1991年第3期216-219,共4页
Academic Journal of Pla Postgraduate Medical School
关键词
LYME病
螺旋体
抗体
蜱
Lyme disease Spirochaetales Antibodies Ticks
