摘要
目的 观察颞颌关节内紊乱(TMJID)病例行关节上腔灌洗后留注透明质酸钠的疗效,并与强的松龙作对照。方法 80例颞颌关节内紊乱病例随机分为两组,生理盐水关节上腔灌洗后吸干,分别注入1ml透明质酸钠和强的松龙,术前,术后1周和4周各记录最大开口度,疼痛指数,弹响及饮食习惯。结果 基于上述四项指标的总有效率,术后1周透明质酸钠组为97.5％(39/40),强的松龙组为82.5％(33/40),统计学上有显著差异(P<0.05);术后4周透明质酸钠组为97.5％(39/40),强的松龙组为77.5％(31/40),统计学有非常显著差异(P<0.01)。透明质酸钠组无1例术后疼痛加剧,强的松龙组有70％(24/40)术后1～3天内出现疼痛加重。结论透明质酸钠是一种可替代类固醇,安全而副作用少的关节功能改善剂。
objective To evaluate the short - term effect of intra - articular injections of sodium hyaluronate (SH) and prednisolone (PL) on patient with TMJ interal derangement. Methods The two drugs were randomly allocated to 80 patients with TMJ interal derangement. After irrigating the super cavity of TMJ with 40ml normal saline, a volume of 1ml of the drug was injected into the super cavity only one time. The patients were assessed maximal interincisal opening, TMJ pain (visual analog scale),TMJ clicking and dietary alterations at preoperatively.one week and 4 weeks postoperativ-ely. ResultsThe results showed that both drugs could reduce the pain scores, increase the maximal interincisal opening, there was statistically difference between two groups after operation one week( P < 0.05 ) and 4 weeks( P < 0. 01). One month postoperatively, the general efficiency of SH - group was decreased from 8.9 to 2.3 , and PL - group was decreased from 8.4 to 3.4 .1-3 days after injection 70% patients of the PL - group felt more painful in joint area , the SH - group had no. ConclusionSodium hyaluronate might be the best alternative drug in treatment of TMJ interral derangement , and could be a substitute for corticosteroid( prednisolone).
出处
《临床口腔医学杂志》
2002年第5期372-373,共2页
Journal of Clinical Stomatology
