摘要
目的对比尿激酶(UK)与肝素治疗不稳定心绞痛(UA)中的疗效。方法采用有对照完全随机化方法。小剂量尿激酶溶栓前增加静脉推注3000U肝素。观察两组心绞痛发作,30天病死率和急性心肌梗塞(AMI)发生率。结果小剂量尿激酶(UK)组在心脏事件(死亡+AMI例数)的发生率低于肝素组,减少频发心绞痛发生率优于肝素组。结论小剂量尿激酶溶栓前加强抗凝血酶治疗,在降低频发心绞痛发生率、30天内AMI发生率和病死率优于肝素组。
Absrtact:Objective:To evaluate the clinical effect of urokinase(UK)in unstable angina(UK).Methods:This was a placebo-controlled randomized clinical trial.In law-dose UK group heparin 3000U iv before thrombolylic therapy. Attack of angina incidences mortity of AMI within 30 days was monitired between the thrombolylic and control groups.Results:In low-does UK group mortity of cariacevent and incidenses of AMI were lower and the number of patient with frequent anigina was significant decrease than the control group.Conclusion:In law-dose UK group enhancing antithrombin therapy before thrombolylic therapy reduced the rate of attack of frequent angia and AMI morthly within 30 days.
出处
《井冈山医专学报》
2002年第6期2-3,共2页
Journal of Jinggangshan Medical College
