摘要
目的 :通过临床病例分析 ,进一步提高对原发性干燥综合征 (pSS)的诊治水平 ,改善预后。方法 :回顾性地分析 1992年 10月~ 2 0 0 0年 5月住我院的pSS病人 32例的临床资料。结果 :pSS以女性患者明显多见 ,男性 1例 ,女性 31例。首发症状和临床表现中 ,口、眼干燥发生率最高 (首发症状中占 81.2 % ,临床表现中占 96 .8% )。有肾小管酸中毒临床表现的发生率为2 8.1% ,有明显肺间质病变者 3例 ,占 9.3% ,血红蛋白降低、血小板降低的发生率分别是 4 6 .8%和 2 5 %。并发恶性淋巴瘤者 1例 ,占 3.1%。结论 :凡在临床上出现不明原因的肾小管酸中毒、贫血、肺间质病变、血小板减少等 ,均要考虑pSS可能 ,而作相应检查 ,以达早期诊治。
Objective: To improve our ability to diagnose and cure the disease of primary sjogren's syndrome by assessing the clinical features of 32 cases of primary sjogren's syndrome. Method: Analyze the 32 cases of primary sjogren's syndrome treated in our hospital from Oct.,1992 to May,2000.Result: In the patients with primary sjogren's syndrome,96.8% appeared dry eyes and dry mouths,which appeared as the first symptoms among 81.2% of them.The rates of other complications such as renal tubular abnormality、interstitial lung disease、anaemia、thrombocytopenia and lymphoma were 28.1%,9.3%,46.8%,25% and 3.1% respectively. The highest rates of the complications were dry eyes and dry mouths. Conclution: In clinic, the primary sjogren's syndrome should be considered if we found that patients had renal tubular abnormalities, anaemia, thrombocytopenia, interstitial lung disease without apparently causes.
出处
《江苏大学学报(医学版)》
CAS
2002年第4期329-330,共2页
Journal of Jiangsu University:Medicine Edition