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慢性肾衰患者的血清阴离子隙与血清白蛋白的关系

Relationship between Serum Anion Gap and Serum Albumin in Patients of Chronic Renal Failure
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摘要 目的 :探讨血清白蛋白对慢性肾衰氮质血症期患者的血清阴离子隙 (AG)的影响。方法 :测定 6 0例慢性肾衰患者的血清 pH、AG、二氧化碳总量、白蛋白、肌酐 ,并用SPSS软件统计分析。结果 :①本组病例呈高AG性代谢性酸中毒并伴有明显低白蛋白血症 ;②慢性肾衰患者的AG与血清白蛋白的降低呈负相关关系。结论 :慢性肾衰患者的AG受血清白蛋白的影响 ,为准确校正AG ,应按血清白蛋白每下降 10 g/L加 2 .5mmol/L。 Objective: To study the relationship between serum anion gap and serum albumin in patients of chronic renal failure. Methods: Serum samples were obtained from 60 cases with chronic renal failure, serum pH, anion gap(AG), total CO 2 , serum albumin, serum creatinine were measured, and analysed by SPSS statistic software. Results: The patients had high AG metabolic acidosis and low serum albumin. AG was inversely correlated with Δ(serum albumin ). Conclusion: In chronic renal failure ,correction of anion gap is well predicted by adding about 2.5mmol/L with 10g/L of Δ(serum albumin)to the measured anion gap.
出处 《中国临床医学》 2002年第4期420-420,423,共2页 Chinese Journal of Clinical Medicine
关键词 阴离子隙 血清白蛋白 慢性肾衰 相关性 Anion gap Serum albumin Chronic renal failure
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参考文献3

  • 1[1]Jurado RL,Del Roi C,Nassar G,et al. Low anion gap. South Med J, 1998, 91:624~629.
  • 2[2]Thomas D, DuBose JR. Acid-base disorders. In Brenner BM, eds. Brenner and Rector ' s the kidney. Harcourt Asia W. B. Saunders,2001:925~997.
  • 3[3]Christos CP, Feifeld DA. A simple estimate of the effect of the serum albumin level on the anion gap. Am J Nephrol, 2000,20: 368~372.

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