摘要
本文依据匡调元提出的体质分型学说,对 Wistar 雄性大鼠筛选寒体与热体。并观察了寒体和热体在能量代谢与内分泌激素方面的差异。实验结果表明:寒体组大鼠在ADK 活性及细胞能荷。肝脏 Na^+-K^+-APTase 活性比热体大鼠低,另外 T_3、T_4、孕酮和睾酮含量方面也比热体大鼠低。可部分论证"体质病理学"一文提出的各型体质必然具有代谢上的差异。并且也提示今后在从事动物实验时应考虑到动物体质的因素。
This paper reports the experimental research on the cold-constitution (CC) and the heat. constitution (HC).The authors have selected the CC and HC in Wistar rats,and have determined adenytate kinase(ADK) activities:energy charge and Na^+-K^+-ATPase activities in liver,the amounts of T_3,T_4,progesterone, testosterone and estradiol in serum,17-KS in urine.The ADK activities were markedly different between the HC group and the CC group (P<0.01).The Na^+-K^+- ATPase activities were obvious different between the HC group and the CC group(P<0.05).The energy charge of the HC group has increased by 16.1% as compared with the CC group in cells.The contents of T_3,T_4 of the HC group were higher than the CC group(P<0.01).The content of progesterone of the HC group was higher than the CC group as well(P<0.01).The contents of E_2 and 17-KS had no differences.These results indicated that differences between the CC and the HC were based on the basic metabolism and its regulators.
基金
国家自然科学基金资助课题
关键词
寒体
热体
腺苷酸激酶
细胞能荷
constitution
adenylate kinase
energy charge
Na^+-K^+-ATPase
thyroxine
progesterone
testosterone
