摘要
对65例充血性心力衰竭(CHF)患者证候进行了临床研究结果发现心气虚是发生 CHF 的根本原因,同时表现出心阴虚证向心阳虚证转化加重的规律和兼夹证逐渐增多的倾向。心阴虚组除血浆醛固酮(pALD)外(P>0.05),血浆心钠素(pANP)和血浆血管紧张素Ⅱ(pAⅡ)均较对照组增高(P<0.05～0.001)。心阳虚组 pANP 和 pALD 较心阴虚组增高(P<0.05～0.005),pA Ⅱ降低(P<0.05)。随心衰加重 pANP 与 pALD 呈正相关(r=0.48,P<0.005).pA Ⅱ与pANP、pALD 呈负相关(r=-0.53,P<0.001)。还就心阴与心阳、心与肾的病理生理学基础进行了讨论。
This paper have carried out clinical study on 65 cases of cpngestive heart failure(CHF).(1)The insufficiency of Heart-Qi(气)was the main cause of invasion of CHF.Along with aggravation of CHF,the Heart Yin(阴)deficiency developed into the Heart Yang(阳)deficiency and-accompanying symptoms multiplied gradually.(2)Except plasma aldosterone(pALD)(P>0.05),the levels of plasma atrial natriuretic polypeptide(pANP)and plasma angiotensin Ⅱ(pAⅡ)in the Heart Yin deficiency group was increased obviously compared with healthy persons(P<0.05～0.001).In the Heart Yang deficiency group,the levels of pANP and pALD was increased markedly(P<0.05～0. 005),the level of pAⅡ was decreased obviously(P<0.05),as compared with the Heart Yin deficiency group.(3)There were positive correlations between pANP and pALD(P<0.005),negative correla- tions between pAⅡ and pANP,pALD(P<0.001).
关键词
充血性
心力衰竭
心气虚证
心钠素
Heart Qi insuffficiency
Heart Y■n deficiency
Heart Yang deficiency
atrial natriuretic polypeptide
aldosterone
angiotensin Ⅱ
congestive heart failure
