摘要
本文以大鼠心肌缺血再灌注为模型,研究当归注射液对再灌性心律失常的保护作用。结果表明,当归注射液腹腔注射(0.6g 生药/kg)能使室性早搏发生率和心律失常总发生率明显减少,与生理盐水对照组比较,差异显著(P<0.05),而与异搏定组比较则差异不显著。提示当归注射液对大鼠心肌缺血再灌注的心律失常具有保护作用。
protective effects of Angelica injection on the reperfusic arrhythmia were studied through the model of ischemic myocardial reperfusion in rats.The results showed that the incidence of ventrictflar premature beat and the total incidence of arrhythmia(IA)were greatly reduced bY peritoneal injection of Angelica (0.6 gm crude drug/kg) in rats.The difference between the Angelica group (n=12,IA=41.7%)and the saline control group (n=12,IA=91.7%)was significant(P<0.05), while that between Angelica group and verapamiI group (n=10,IA=40%) was insignificant (P>0. 05).The data suggested that Angelica injection is effective on the protection of arrhythmia during the myocardial ischemia reperfusion in rats.
出处
《中西医结合杂志》
CAS
CSCD
北大核心
1991年第6期360-361,共2页
关键词
当归注射液
心肌缺血
再灌注
大鼠
Angelica
Verapamil
myocardial ischemia
reperfusion
rat
