摘要
介绍用日立型氨基酸自动分析仪测定烧伤30%兔血浆,红细胞和各种组织的游离氨基酸含量。结果表明:烧伤后86%～87%远离烧伤部位的骨骼肌、肝脏和肺组织、80%～82%脑、骨髓和红细胞、73%心肌、肾脏、脾脏和57%痂下骨骼肌的游离氨基酸浓度变化趋势与血浆的相似。提示:烧伤后血浆游离氨基酸谱的变化基本上能代表体内总游离氨基酸库的变化,是烧伤营养研究的有用指标。
Free amino acid(FAA)levels in plasma,erythrocytes,bone marrow,skeletal muscle, heart,liver,lung,brain,kidney and spleen were measured simultaneously in rabbits with burn injury.Results of study showed that,86%-87% of skeletal muscle(remote from burn site), liver and lung FAA,80%-82% of brain,bone marrow and erythrocyte FAA,73% of heart, spleen and kidney FAA,and 57% of skeletal muscle(underneath the burn site)FAA varied in levels with the trends similar to that in plasma.These results suggest that the changes in profile of plasma free amino acids may essentially represent that of total amino acid pool after burn injury,and that the plasma amino acid kinetics seems to be a useful index for clini- cal study.
