摘要
目的 探讨与胆石症有关的危险因素。方法 对合肥市区 1998年 8月～ 12月间的 34 1例胆石症新发病人进行 1:1配对病例对照研究 ,采用条件 L ogistic回归分析。结果 男性 :服治疗冠心病的药物 (OR =5 .30 ,95 % CI:2 .2 0～ 8.33) ;体重指数 (OR =1.97,OR 95 % CI=1.2 6～3.41) ;女性 :绝经年数 (OR =2 .6 7,OR 95 % CI=1.75～ 5 .0 0 ) ;孕次 (OR=1.71,OR 95 % CI=1.2 6～ 3.0 1) ;就寝时间 (OR =0 .6 3,OR 95 % CI=0 .2 5～ 0 .92 ) ;2 5 a以后体重变化 OR =1.43,OR 95 % CI=1.0 3～ 3.43。结论 肥胖和多次妊娠仍是胆石症的危险因素 ;男、女胆石症的危险因素有差别。肥胖和治疗冠心病的药可能是男性胆石症的危险因素 ;2 5 a以后体重明显增加、2 2时以前就寝、绝经年数及多次妊娠可能是女性胆石症的危险因素。
Objective To study the risk factors of gallstone disease. Methods 1:1 matched case-control study was conducted through 341 patients with gallstone and controls from hospitals. Conditional logistic regression analysis was used. Results For male, OR of taking drugs for coronary heart disease is 5.30 ( OR 95%CI=2.2~8.33), OR of body mass index is 1.97 ( OR 95%CI=1.26~3.41); for female, OR of years of postmenopause is 2.67 ( OR 95%CI=1.75~ 5.00 ), OR of pregnancy number is 1.71 ( OR 95%CI=1.26~3.01), OR of time for going to bed at night is 0.63 ( OR 95%CI=0.25~0.92), OR of body weight change since age 25 is 1.43 ( OR 95%CI=1.03~3.43). Conclusions Obesity and fertility are still the main risk factors for gallstone disease. The risk factors may be different between the male and the female. Obesity and taking drugs for coronary heart disease may be risky for the male. The years of postmenopause, fertility , body weight increase after age 25 and sleeping before 22 at night may be risk factors of gallstone disease for female.
出处
《疾病控制杂志》
2002年第3期233-235,共3页
Chinese Journal of Disease Control and Prevention
