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大肠埃希菌在肿瘤患者肠外的分布及耐药谱分析 被引量:2

THE DISTRIBUTION OF ESCHERICHIA COLI IN THE EXOINTESTION OF PATIENTS WITH MALIGNANT TUMORS AND ANALYSIS OF ITS DRUG RESISTANCE
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摘要 目的 :了解大肠埃希菌在肿瘤患者肠外的分布和感染情况及耐药性。方法 :参照全国临床检验操作规程 ,采用 K- B法对云南省肿瘤医院 5 8例肿瘤患者继发大肠埃希菌感染进行分析及对 9种抗生素的耐药谱测定。结果 :各类肿瘤患者中 ,以宫颈癌及继发大肠埃希菌感染多见 ,其中 ,宫颈癌为 2 8.30 % ,肺癌为 2 6 .87% ;从标本来源来看 ,以尿液标本最多 ,为 6 3.79% ,其次为痰液 12 .0 7%及分泌物 12 .0 7%。结论 :大肠埃希菌在肿瘤患者肠外分布广泛 ,所致感染较严重。经耐药谱测定发现大肠埃希菌多重耐药类型多 。 Objective:To study the infection caused by Escherichia coli in the patients with malignant tumors and its drug resistance. Methods:58 patients with malignant tumors,from Yunnan Tumor Hospital,who had secondary infection caused by Escherichia coli ,were studide and the drug resistance of Escherichia coli to 9 antibiotics was examined,according to the standard operating rules and the Kirby Bauer's method.Results:In all kinds of patients with malignant tumors,the rate of secondary infection by Escherichia coli is higher for hte cervical carcinoma patients and the lung cancer patients than that for patients with other tumors.The infection rate of cervical carcinoma patients is 28.30% and the rate of lung cancer patients is 26.87%;According to the source of the samples,the ratio was the highest in urine samples,both being 12.07%. Conclusion:The distribution of Escherichia coli in the exointestines of patients with malignant tumors was extensive.The infection caused by Escherichia coli was severe.According to the result of drug resistance examination,it was seen that the Escherichia coli had a multi drug resistance.So the treatment to the patients with malignant tumors should attach importance to the balance of microecology and control of the infection.
作者 何亮 陈群
出处 《中国微生态学杂志》 CAS CSCD 2002年第4期225-226,共2页 Chinese Journal of Microecology
关键词 大肠埃希菌 肿瘤患者 肠外 分布 耐药谱分析 Tumor Distribution of Escherichia coli Drug resistance
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