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铅暴露的男性生殖毒理流行病学研究 被引量:14

Toxicological & Epidemiological Studies on the Reproductive Abilities of Male Workers Exposed to Lead
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摘要 本文以流行病学方法调查了24名铅作业男工并以年龄、吸烟、饮酒为均衡条件,配对调查了24名正常男性的生殖功能。结果表明:铅作业组的尿铅浓度、先天性癫痫及先天性心脏病患病率、精子畸形率显著高于正常组。并讨论了铅作业组的精子计数和活力下降与精子乳酸脱氢酶和琥珀酸脱氢酶的活性均受抑制的关系。 The reproductive ability of 24 workers exposed to lead was observed withthe same number of no-exposed men as controls.All influential factors,such asage,smoking and drinking were matched closely.The finding shows higherprevalence of congenital epilepsy and heart disease in the filial generation andhigh rate of teratospermia in the exposed workers.A relationship betweenoligospermia and inhibition of lactate dehydrogenase (LDH-x) andsuccinodehydrogenase (SDH) activities of the exposed group was discussed.
出处 《中华劳动卫生职业病杂志》 CAS CSCD 1991年第3期137-140,共4页 Chinese Journal of Industrial Hygiene and Occupational Diseases
关键词 生殖 毒理 流行病学 Lead Reproductive toxicology sperm Infertility
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参考文献3

  • 1马青平等.实用男性学[M]天津科学技术出版社,1988.
  • 2杨树勤.卫生统计学[M]人民卫生出版社,1978.
  • 3B. P. Eyden,J. R. Maisin,G. Mattelin. Long-term effects of dietary lead acetate on survival, body weight and seminal cytology in mice[J] 1978,Bulletin of Environmental Contamination and Toxicology(1):266~272

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