摘要
目的 观察 2型糖尿病患者空腹糖化血清蛋白 (GSP)和空腹及餐后血清游离脂肪酸 (FFA)的变化 ,进一步探讨 2型糖尿病患者血清 GSP和 FFA的变化及临床意义。方法 选择 2型糖尿病 87例、对照组 4 6例 ,采用葡萄糖己糖激酶法测定空腹和餐后 2小时血糖 ;酮胺氧化酶法测定空腹 GSP;酶比色法测定空腹 FFA和餐后 2小时 FFA水平。结果 12型糖尿病组的空腹 GSP及餐后 2小时的血糖、FFA较正常对照组有显著性差异 ,(P<0 .0 5 )。 2 2型糖尿病组的餐后 2小时 FFA与空腹 FFA比较水平有所下降。 32型糖尿病组的空腹血糖和餐后 2小时血糖与 FFA及 GSP浓度均呈正相关 (r=0 .84 4 2和 r=0 .832 9,P<0 .0 0 1;r=0 .5 94 4和 r=0 .5 5 93P<0 .0 0 1)。结论 GSP和 FFA的测定对糖尿病的病情监控及并发症防治具有重要意义。
Objective To observe the variation of GSP and FFA in type 2 diabetic patients (T 2DM) before and two hours after diet and their clinical significances.Methods Blood glucose in 87 patients and 46 cases of control group was measured by Hexokinasa method.GSP and FFA were detected by KAO method and enzyme colour method respectively.Results ①There were significant differences between T 2DM and normal controls in GSP and fasting and postprandial FFA( P <0.01).②The level of postprandial FFA was lower than that of fasting.③There was a positive association between blood glucose and FFA(r=0.8842,r=0.8329, P <0.01) and also GSP(r=0.5944,r=0.5933, P <0.001).Conclusion GSP and FFA are important for the detection of T 2DM and its complications.
出处
《四川医学》
CAS
2002年第9期890-891,共2页
Sichuan Medical Journal
