摘要
目的分析上海奉贤东部地区儿童呼吸道细菌感染与支原体感染情况及临床治疗效果。方法选取2016年-2017年因呼吸道感染疾病于医院进行治疗的2 468例患儿,其中呼吸道细菌感染与支原体感染的患儿共336例,对比两组患儿感染发生率上的差异。结果 2 468例患儿中,检出存在呼吸道细菌感染与支原体感染的患儿共336例,占13.61%;呼吸道细菌感染患儿共178例,占7.21%;支原体感染患儿共184例,占7.46%;26例患儿存在双重感染,占1.05%。统计发现,呼吸道细菌感染患儿在各个年份上半年与下半年发病存在显著差异(P<0.05);336例呼吸道细菌感染与支原体感染患儿以支气管肺炎感染最高,分别为55.06%(98/178)与62.50%(115/184);急性支气管感染分别为30.90%(55/178)与23.37%(43/184);呼吸道细菌感染患儿治疗有效率90.45%,支原体感染患儿治疗有效率86.41%,两组疗效无显著差异。结论呼吸道细菌感染与支原体感染主要引起患儿出现支气管肺炎与急性支气管炎,临床中采用哌拉西林/他唑巴坦进行治疗有显著疗效。
OBJECTIVE To investigate the prevalence of respiratory tract bacterial infection and Mycoplasmainfection in children of eastern Fengxian,Shanghai and analyze the clinical curative effects.METHODS A total of 2468 children who were treated in the hospital due to respiratory tract infectious diseases from 2016 to 2017 were enrolled in the study,336 of whom had respiratory tract bacterial infection and Mycoplasmainfection,and the incidence of infection was compared between the two groups of children.RESULTS Of the 2468 children,336 had respiratory tract bacterial infection and Mycoplasma infection,accounted for 13.61%;totally 178 children had respiratory tract bacterial infection,accounted for 7.21%;totally 184 children had Mycoplasmainfection,accounted for 7.46%;26 children had double infection,accounting for 1.05%.The univariate analysis showed that there was significant difference in the mortality among the children with respiratory tract bacterial infection in the first half year and second half year of 2016 and 2017（P〈0.05）.Among the 336 children,55.06%（98/178）had bronchial pneumonia among the children with respiratory tract bacterial infection,and 62.50%（115/184）had bronchial pneumonia among the children with Mycoplasmainfection;the children who had acute bronchial infection accounted for 30.90%（55/178）and 23.37%（43/184）.The effective rate of treatment of the children with respiratory tract bacterial infection was 90.45%,the effective rate of treatment of the children with Mycoplasmainfection was86.41%,and there was no significant difference in the curative effect between the two groups（P〈0.05）.CONCLUSION The respiratory tract bacterial infection and Mycoplasmainfection are the leading causes of bronchial pneumonia and acute bronchial pneumonia in the children.Piperacillin-tazobactam can achieve remarkable curative effect.
作者
邬巍
李恒涛
王根在
查建忠
林束珠
朱洪庆
张瑞霞
WU Wei;LI Heng-tao;WANG Gen-zai;ZHA Jian-zhong;LIN Shu-zhu;ZHU Hong-qing;ZHANG Rui-xia(Fengcheng Hospital of Shanghai Fengxian District,Shanghai 201411,China)
出处
《中华医院感染学杂志》
CAS
CSCD
北大核心
2018年第22期3490-3493,共4页
Chinese Journal of Nosocomiology
基金
上海市卫生和计划生育委员会科研基金资助项目(201640299)
关键词
呼吸道细菌感染
支原体感染
双重感染
季节气候
Respiratory tract bacterial infection
Mycoplasma infections Double infections Seasonal climate
