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EPO联合左卡尼汀对肾性贫血患者内皮素和左室重构的影响 被引量:2

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摘要 目的:观察促红细胞生成素联合左卡尼汀治疗肾性贫血对内皮素和左室重构的影响。方法:选取2015年6月~2017年6月在我院诊治的尿毒症肾性贫血患者116例为研究对象,随机分为对照组和观察组,对照组患者给予重组人促红细胞生成素治疗,观察组给予重组人促红细胞生成素联合左卡尼汀治疗。观察两组治疗前后Hb、HCT、ET水平,LVDd、LVDs、LAD大小,统计重组人促红细胞生成素用量及不良反应发生情况。结果:治疗后,观察组Hb、HCT水平明显高于对照组,ET水平低于对照组,P<0.05;治疗后,观察组LVDd、LVDs、LAD均明显低于对照组,P<0.05;观察组重组人促红细胞生成素用量及不良反应发生率均明显低于对照组,P<0.05,差异有统计学意义。结论:促红细胞生成素联合左卡尼汀治疗可有效纠正肾性贫血,降低血浆内皮素水平,抑制左心室重构的发生或进展,减少心血管事件的发生风险,且安全性较高,临床价值显著。
作者 孙婷婷
出处 《实用中西医结合临床》 2018年第8期23-25,共3页 Practical Clinical Journal of Integrated Traditional Chinese and Western Medicine
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