摘要
目的研究男性阻塞性睡眠呼吸暂停低通气综合征(obstructive sleep apnea hypopnea syndrome,OSAHS)患者快速眼动(rapid eye movement,REM)睡眠的特点,探究睡眠呼吸暂停低通气指数(AHI)与男性REM睡眠的关系及临床意义。方法收集1235例在北京大学第三医院耳鼻咽喉科接受多导睡眠监测的男性个体,根据睡眠呼吸暂停低通气指数(AHI)分为正常对照、轻度、中度及重度4组,比较组间REM时长及所占比例。结果男性正常对照组REM期睡眠占总睡眠时长比例为(12. 36±6. 05)%,轻度OSAHS组为(11. 97±6. 53)%,中度OSAHS组为(11. 26±5. 58)%,重度OSAHS组为(8. 73±5. 32)%。随着AHI每增加10次/h,REM所占比例逐渐减少0. 75%,且重度OSAHS患者REM期睡眠剥夺较轻中度组更为明显,差异具有统计学意义(P <0. 001)。结论男性OSAHS患者随着AHI增加,REM睡眠减少,睡眠结构紊乱加重,且在重度OSAHS患者中更为显著。
Objective To study the characteristics of rapid eye movement（REM）sleep in male patients with obstructive sleep apnea hypopnea syndrome（OSAHS）and explore their relationships with apnea hypopnea index（AHI）obtained by polysomnography（PSG）.MethodsA total of 1235 male subjects undergoing PSG in our department were included.According to the AHI,they were divided into normal control group,mild and moderate as well as severe OSAHS groups.The duration and percentage of REM sleep were compared among the four groups.ResultsThe percentage of REM sleep was（12.36±6.05）%in the control group,（11.97±6.53）%in the mild OSAHS group,（11.26±5.58）%in the moderate group,（8.73±5.32）%in the severe group,respectively.Each additional 10 times/h of AHI was associated with a 0.75%decreased percentage of REM sleep.REM sleep deprivation in the severe OSAHS group was more obvious than those in both the mild and moderate groups,and the differences were statistically significant（both P〈0.001）.ConclusionWith the increase of AHI,the percentage of REM sleep gets decreased and sleep architecture disorder is aggravated in male patients with OSAHS,especially in those with severe OSAHS.
作者
曾进
闫燕
古雅兰
王丽
ZENG Jin;YAN Yan;GU Ya-lan;WANG Li(Department of Otolaryngology,the Third Hospital of Peking University,Beijing 100191,China)
出处
《中国耳鼻咽喉颅底外科杂志》
CAS
2018年第5期413-416,共4页
Chinese Journal of Otorhinolaryngology-skull Base Surgery
基金
北京大学第三医院临床重点项目(71490-3)
