摘要
目的探讨不同微创术式治疗高龄直肠癌病人的疗效及对其免疫炎性反应及预后的影响分析。方法选取我科收治的80例直肠癌高龄病人,根据手术治疗方式的不同,分为研究组及对照组两组(各40例),研究组采用单孔腹腔镜直肠癌手术治疗,对照组采用采用传统多孔腹腔镜直肠癌手术治疗。比较两组病人的临床疗效等差异。结果研究组病人的切口长度(2. 8±0. 4) cm、住院时间(7. 9±1. 8)天、术后首次排气时间(2. 6±1. 4)天及术后VAS评分(2. 6±0. 4)分均显著少于对照组,而手术时间(180. 2±7. 2)分钟,长于对照组病人(144. 5±7. 5)分钟(P <0. 05);研究组病人的术后并发症率(7. 5%)与对照组病人(12. 5%)比较无统计学差异(P>0. 05);研究组病人的免疫炎性指标均较对照组改善明显(P <0. 05);两组病人术后1年生存率(87. 5%vs 85. 0%)及复发率(5. 0%vs 7. 5%)的差异情况比较无差异(P> 0. 05)。结论单孔腹腔镜下治疗高龄直肠癌病人的预后与多孔腹腔镜无差异,但可减轻术后免疫应激反应,手术适应证需严格把控。
Objective To investigate the comparison of clinical efficacy、immune inflammatory response and prognosis of single port laparoscopic radical surgery and routine laparoscopic radical resection for rectal cancer of old patients. Methods To screening 80 cases of old patients with rectal cancer as research subjects,it will be divided into study group with 40 cases and control group with 40 cases,patients in control group were given routine laparoscopic radical resection treatment and patients in study group were given single port laparoscopic radical surgery,then the two groups were compared in terms of clinical efficacy and so on. Results The slash length（ 2. 8 ± 0. 4） cm,hospital stays（ 7. 9 ± 1. 8） d,postoperative first exhaust time（ 2. 6 ± 1. 4） d and postoperative VAS score（ 2. 6 ± 0. 4） in study group were better than the control group（ P〈0. 05）; There was no significance difference between study group and control group in postoperative complications rate（ 7. 5% vs 12. 5%,P〈0. 05）; The immune inflammatory response indexes were all better in study group than in the control group after the treatment（ P〈0. 05）;There had no significance difference between study group and control group in 1 year survival rate（ 87. 5%vs 85. 0%） and recurrence rate（ 5. 0% vs 7. 5%） after operation（ P〉0. 05）. Conclusion The single port laparoscopic radical surgery in the treatment of old patients with rectal cancer is significant,but must strictly control the surgical indications.
作者
曹金鹏
杨平
余思
李志澄
朱佳成
罗特东
计勇
CAO Jinpeng;YANG Ping;YU Si(Department of Gastrointestinal Surgery 1,the First people s Hospital of Foshan City,Guangdong Province,Foshan 528000,China)
出处
《临床外科杂志》
2018年第10期751-753,共3页
Journal of Clinical Surgery
基金
广东省医学科研基金资助项目(A2013665)
关键词
高龄直肠癌
单孔腹腔镜
免疫炎性反应
预后
old patients with rectal cancer
single port laparoscopic radical surgery
immune inflammatory response
prognosis
