摘要
目的回顾性分析抗中性粒细胞胞质抗体相关性血管炎患者的临床特点及预后。方法检索安徽医科大学第二附属医院住院系统数据库,回顾性分析2012年8月至2016年6月102例ANCA相关性血管炎住院患者的临床资料。结果 (1)男40例,女62例,平均年龄68岁。ANCA相关性血管炎表现为多器官受累,肾脏和肺受累最多见。(2)预后:102例随访患者中,有12例患者失访。其中治疗后诱导缓解有38例(42.22%),血液透析10例(11.11%),腹膜透析6例(6.67%),随访期间死亡有36例(40.00%)(死亡原因为重症肺炎15例,心血管意外13例,败血症2例)。结论 ANCA相关性血管炎最常累及器官前两位分别是肾脏和肺。该类患者死亡原因前两位分别是重症肺炎和心血管疾病。
Objective to review and analyze clinical characteristics and prognosis of patients with anti neutrophil cytoplasmic antibody associated vasculitis. Methods retrieve database of hospitalization system of Anhui Medical University the Second Affiliated Hospital, review and analyze clinical data of 102 cases ANCA associated vasculitis patients from August 2012 to June 2016. Results（1） there were 40 males and 62 females with average age of 68. ANCA associated vasculitis showed characteristics of multiple organ involvement, mostly with kidney and lung involvement.（2） Prognosis： 12 out of 102 follow-up patients were lost connection. 38 cases（42.22%） with induced remission, 10 cases hemodialysis（11.11%）, 6 cases peritoneal dialysis（6.67%）, 36 cases（40.00%） died during follow-up period（15 cases of severe pneumonia, 13 cases cardiovascular accident, 2 cases septicemia）. Conclusion most frequently involved organs of ANCA associated vasculitis are kidney and lung, death causes of patients were severe pneumonia and cardiovascular disease respectively.
作者
张超
王德光
郝丽
ZHANG Chao;WANG De-guang;HAO Li(Nephrology Department,Anhui Medical University the Second Affiliated Hospital,Hefei,Anhui,230601)
出处
《智慧健康》
2018年第15期46-47,共2页
Smart Healthcare
关键词
血管炎
抗中性粒细胞胞质抗体
临床特点
预后
Vasculitis
Anti neutrophil cytoplasmic antibody
Clinical characteristics
Prognosis
