摘要
随着痛风发病率的逐年升高,痛风疾病的难愈性和反复发作性已成为当前临床治疗的主要问题和难点。目前使用的抗痛风西药降低尿酸和控制炎性反应在短期内疗效肯定,但长期应用会导致诸多不良反应。土茯苓作为一种传统中药,临床上可用于治疗痛风,其效果显著且不良反应少。本文将土茯苓主要化学成分以及治疗痛风作用的机制作一综述,为将其研究开发成为抗痛风药物提供参考。
As the morbidity rate of gout increase significantly year by year,the refractory and the recurrent nature of gout has become the main problems and difficulty in clinical treatment. Currently, the application of anti-gout western medicine results effectively in inflammation controlling and uric acid reduction. However, the long-term application nfight lead to many adverse reactions. Glabrous Greenbrier Rhizome, as a kind of common traditional Chinese medicine, has remarkable effects in clinical treatment of gout,with little side effects. This paper reviewed some progresses on chenfical constituents and anti-gout mechanism of Glabrous Greenbrier Rhizome, aiming at providing references for its research and development into anti-gout drugs.
作者
梁巧静
梁维萍
李琼
郭宏伟
朱丹
Liang Qiaojing;Liang Weiping;Li Qiong;Guo Hongwei;Zhu Dan(College of Pharmacy,Guangxi Medical University,Nanning 530021,China;Key Laboratory of Longevity and Aging-related Disease,Chinse Ministry of Education,Nanning 530021,China;Center for Translational Medicine,Guangxi Medical University,Nanning 530021,China)
出处
《世界中医药》
CAS
2018年第11期2937-2940,共4页
World Chinese Medicine
基金
广西科学研究与技术开发计划项目(桂科攻1598013-8)--壮药配方雷公降压颗粒的研制
关键词
土茯苓
痛风
高尿酸血症
痛风性关节炎
高尿酸血症肾病
化学成分
作用机制
研究进展
Glabrous Greenbrier Rhizome
Gout
Hyperuricemia
Gout arthritis
Hyperuricemic nephropathy
Chemical component
Mechanism
Research progress
