摘要
目的回顾性分析老年心房颤动(atrial fibrillation,AF)病人血尿酸(UA)浓度,探讨老年AF与UA之间关系。方法收集566例住院病人基本临床资料,分别根据是否有AF和UA浓度高低分为AF与非AF组、高尿酸血症与非高尿酸血症组,检测各组病人的左心房(left atrium,LA)内径、右心房(right atrium,RA)内径,同时观察各组合并症情况。结果 AF组左LA和RA内径明显大于非AF组,合并高尿酸血症、冠心病(coronary heart disease,CHD)、原发性高血压(EH)的例数均多于非AF组,2组比较差异有统计学意义(P<0. 05或P<0. 01)。高尿酸血症组LA和RA内径均大于非高尿酸血症组,合并EH、缺血性脑卒中、AF的例数均多于非高尿酸血症组,差异均有统计学意义(P<0. 05或P<0. 01)。Logistic回归分析显示,合并CHD、RA内径、高尿酸血症是老年AF的独立影响因素。结论老年AF与高尿酸症之间存在关联,高尿酸血症可能是老年AF的危险因素之一。
Objective To retrospectively analyze the serum uric acid（ UA） level in the patients with atrial fibrillation（ AF）,and to investigate the relationship between UA and AF. Methods The clinical data of 566 hospitalized patients were enrolled. The patients were grouped according to whether they had AF or not and the serum level of UA. The internal diameters of left atrium（ LA） and right atrium（ RA） were detected,and the complications were observed in different groups. Results The internal diameters of LA and RA were significantly bigger and the cases complicated with hyperuricemia,coronary heart disease（ CHD）,essential hypertension（ EH） were significantly more in AF group than those in nonAF gruop（ P〈0. 05 or P〈0. 01）. The internal diameters of LA and RA were significantly bigger and the cases complicated with EH,cerebral ischemic stroke and AF were significantly more in hyperuricemia group than those in non-hyperuricemia gruop（ P〈0. 05 or P〈0. 01）.Logistic congression analysis showed that CHD, internal diameters of RA, hyperuricemia were associated with AF in the elderly.Conclusions hyperuricemia may be one of the risk factors for AF in the elderly patients.
作者
纪禹同
冯国飞
董凤英
谢志泉
JI Yu-tong;FENG Guo-fei;DONG Feng-ying;XIE Zhi-quan(Department of Geriatric Cardiology,General Hospital of Guangzhou Military Aera Command,Guangzhou 510010,China)
出处
《实用老年医学》
CAS
2018年第10期954-957,共4页
Practical Geriatrics
