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骨折和骨折术后应激性溃疡 被引量:4

Stress Ulcer Resulting from Fracture and Its internal Fixation
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摘要 本文报告10例骨折和骨折术后应激性溃疡。7例由严重骨折引起3例由骨折内固定手术引起。5例胃镜检查及2例术中检查均证实胃粘膜有糜烂和溃疡。7例积极内科治疗奏效,手术2例。死亡1例。本文讨论了该病的发病机理,指出内窥镜检查是不可缺少的诊断步骤,经内科积极治疗无效者应果断采用手术止血。 Ten cases of stress ulcer were seen from 1979 to 1988 after fracture, 7 after serious fracture and 3 after open reduction and internal fixation. Gastrointestinal tract bleeding appeared 2-10 day after injury. Diagnosis was confirmed through gastroscope in 5 cases and exploratomy laparotomy in 2 cases. Erosion and ulcer formation of the gastric mucous membrane was found during operation. Conservative treatment was adopted with success. Partial gastrectomy with selective vagotomy (or additional suture ligation) were done in the 2 other cases with recovery when conservative treatment proved failure. One died. Pathogenesis of stress ulcer is discussed. Endoscopy was recommended for diagnosis. If conservative method proved failure, surgical procedure should be performed for prompt hemostasis.
作者 李明祚
出处 《中华创伤杂志》 CAS CSCD 北大核心 1991年第2期80-82,共3页 Chinese Journal of Trauma
关键词 应激性溃疡 骨折 细胞保护 stress ulcer fracture
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参考文献2

  • 1汪鸿志,麻树人.纤维内窥镜对急性上消化道大出血的诊断价值(附251例病因分析)[J]解放军医学杂志,1980(04).
  • 2Frank G. Moody M.D.,Charlotte A. Zalewsky Ph.D.,Kenneth R. Larsen Ph.D.. Cytoprotection of the gastric epithelium[J] 1981,World Journal of Surgery(2):153~163

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