摘要
目的:观察中西医结合对早期糖尿病足的治疗效果。方法:选取240例早期糖尿病足患者,按随机数字表法分为空白组、西药组、中西医结合组。空白组仅单纯控制血糖,西药组在空白组基础上给予甲钴胺胶囊,中西医结合组在西药组的基础上,辨证给予内服降糖方,外用中药熏洗。观察并比较3组一般情况、踝肱指数、糖化血红蛋白(Hb A1c)、空腹血糖(FBG)、餐后2 h血糖(P2h BG)等指标。结果:与空白组比较,西药组、中西医结合组总有效率较高,差异均有统计学意义(P <0.05)。与西药组比较,中西医结合组总有效率较高,差异有统计学意义(P <0.05)。与同组治疗前比较,3组FBG、P2hBG、Hb A1c显著降低,差异均有统计学意义(P <0.05)。治疗后,空白组、西药组及中西医结合组FBG、P2hBG、HbA1c比较,差异无统计学意义(P> 0.05)。治疗后,与空白组比较,西药组及中西医结合组踝肱指数显著升高,差异均有统计学意义(P <0.05);中西医结合组踝肱指数显著高于西药组(P <0.05)。结论:中西医结合治疗早期糖尿病足能明显改善症状,有良好的临床疗效,值得临床推广。
Objective： To observe the clinical effect of integrated Chinese and western medicine therapy for diabetic foot in early stage. Methods： Selected 240 cases of patients with diabetic foot in early stage and divided them into the blank group, the western medicine group,and the integrated Chinese and western medicine therapy group according to random number table method. The blank group only received the simple control of the blood glucose,and the western medicine group received mecobalamin capsules based on the treatment of the blank group. On the basis of the treatment of the western medicine group, the integrated Chinese and western medicine therapy group received Jiangtang prescription orally based on syndrome differentiation and was given external application of fumigation and washing of Chinese medicine. Observed and compared the general condition, ankle-brachial index and levels of glycosylated hemoglobin（HbA1c）,fasting blood glucose（FBG） and postprandial 2 h blood glucose（P2hBG） in the three groups. Results：Compared with those in the blank group,the total effective rates in the western medicine group and the integrated Chinese and western medicine therapy group were higher,differences being significant（P〈0.05）. Compared with those in the western medicine group,the total effective rate in the integrated Chinese and western medicine therapy group was higher,the difference being significant（P〈0.05）.Compared with those in the same group before treatment, levels of FBG, P2hBG, HbA1c in the three groups were significantly decreased,differences being significant（P〈0.05）. After treatment,no significant difference was found in the comparisons of the levels of FBG,P2hBG,HbA1c between the three groups（P〉0.05）. After treatment,the ankle-brachial index in the western medicine group and the integrated Chinese and western medicine therapy group was significantly increased when compared with that in the blank group,differences being significant（P〈0.05）. The ankle-brachial index in the integrated Chinese and western medicine therapy group was significantly higher than that in the western medicine group（P〈0.05）. Conclusion：Integrated Chinese and western medicine therapy for diabetic foot in early stage can obviously improve the symptoms with significant clinical effect,which is worthy of promotion in clinical practice.
作者
李蔚
宁雪峰
孙丹凤
王晶
范力
李雯雯
邢鹏超
LI Wei;NING Xuefeng;SUN Danfeng;WANG Jing;FAN Li;LI Wenwen;XING Pengchao
出处
《新中医》
CAS
2018年第10期86-89,共4页
New Chinese Medicine
基金
甘肃省中医药管理局科研课题(GZK-2014-66)
关键词
早期糖尿病足
中西医结合
甲钴胺
降糖方
中药熏洗
踝肱指数
Diabetic foot in early stage
Integrated Chinese and western medicine
Mecobalamin
Jiangtangprescription
Fumigation and washing of Chinese medicine
Ankle-brachial index
