摘要
目的:探讨富血小板血浆(PRP)联合头颈开窗髂骨植骨治疗股骨头坏死的临床疗效。方法:2015年9月至2017年2月,采取前瞻临床随机对照研究,对44例ARCOⅡ-Ⅲ期股骨头坏死患者进行研究。其中观察组22例,采用经股骨头颈部开窗髂骨植骨术,配合术后髋关节PRP注射治疗。对照组22例,仅给予经股骨头颈部开窗髂骨植骨术。记录两组患者术前VAS评分和Harris评分。术后定期随访,记录两组患者术后1年VAS评分和Harris评分,并根据术后1年影像学进展情况计算改善率。结果:所有44例髋术后均未发生感染、神经血管损伤等术后并发症,所有病例均获得随访。两组患者术后1年的VAS评分和Harris评分与术前比较,差异有统计学意义(P<0.05)。术后1年VAS评分,两组间比较差异无统计学意义(P>0.05)。术后1年Harris评分,观察组优于对照组,差异有统计学意义(P<0.05)。术后1年,观察组股骨头坏死改善率90.90%高于对照组的63.64%.结论:富血小板血浆联合头颈开窗髂骨植骨治疗股骨头坏死疗效确切,髋关节功能改善明显,是一种较好的保髋治疗手段。
Objective：To evaluate the clinical effects of opening bone grafting in head and neck combined with platelet-rich plasma for treating osteonecrosis of femoral head.Methods：From September 2015 to February 2017,44 patients with stageⅡ-Ⅲ（ARCO）osteonecrosis of femoral head were studied.Twenty-two cases were in the observation group and 22 cases were in the control group.The observation group adopted opening bone grafting in head and neck combined with platelet-rich plasma,while the control group adopted opening bone grafting in head and neck.The two groups were compared before and after the surgery by Harris scores,VAS scores and imaging changes.Results：There were no complications of dislocation,periprosthetic fracture and infection within 12 months after surgery.Compared to the data before the treatment,VAS scores and Harris scores at one-year follow-up in both groups showed better outcomes（P〈0.05）.The VAS scores of the observation group was lower than that of the control group,but there was no significant difference between them（P〉0.05）.Harris score was better than the control group,with statistically significant difference（P〈0.05）.The rate of necrosis of femoral head in the observation group was 90.90%,which was higher than 63.64%in the control group（P〈0.05）.Conclusion：The effect of opening bone grafting in head and neck combined with platelet-rich plasma in the treatment of osteonecrosis of femoral head is accurate,and the improvement of hip function is obvious,which is a better means of hip treatment.
作者
朱晓龙
邹德宝
鞠昌军
严伟
李磊
余昕
张亚霖
金鑫
姜红江
ZHU Xiaolong;ZOU Debao;JU Changjun;YAN Wei;LI Lei;YU Xin;ZHANG Yalin;JIN Xin;JIANG Hongjiang(Anhui University of Traditional Chinese Medicine,Hefei 230000,Shandong China;Shandong Wendeng Orthopedics Hospital,Wendeng 264400,Shandong China)
出处
《中国中医骨伤科杂志》
CAS
2018年第10期36-39,44,共5页
Chinese Journal of Traditional Medical Traumatology & Orthopedics
关键词
股骨头坏死
富血小板血浆
治疗
femur head necrosis
platelet-rich plasma
therapeutics
