摘要
目的:探讨中药三联疗法对慢性盆腔炎血清炎性指标及血液流变学的影响,进而指导临床应用。方法:选取我院2016年3月—2018年3月收治的慢性盆腔炎患者124例,所有患者按照数字随机分组原则分为西药组和中药组各62例,西药组患者给予头孢拉定胶囊口服+微波照射物理治疗+替硝唑注射液灌肠三联疗法,中药组患者给予中药口服+中药热敷+中药灌肠三联疗法。结果:治疗后,西药组和中药组TNF-a、CRP、IL-1β以及IL-6均明显下降,与治疗前比较,差异显著(P<0.05);治疗后,中药组TNF-a、CRP、IL-1β以及IL-6均明显低于西药组,差异显著(P<0.05);治疗后,西药组和中药组血细胞比容、红细胞沉降率、全血高切黏度以及全血低切黏度均明显下降,与治疗前比较,差异显著(P<0.05);治疗后,中药组血细胞比容、红细胞沉降率、全血高切黏度以及全血低切黏度均明显低于西药组,差异显著(P<0.05)。结论:中药三联疗法可有效改善慢性盆腔炎患者血液流变学指标,缓解患者的炎性反应,临床应用价值较高。
Objective： To investigate the effect of TCM triple therapy on serum inflammatory indexes and hemorheology of chronic pelvic inflammatory disease, and guide the clinical application. Methods： 124 patients with chronic pelvic inflammation selected from March 2016 to March 2018 in our hospital were divided into western medicine group and traditional Chinese medicine group according to the principle of random grouping. The western medicine group was given Cefradine capsule orally ＋ microwave irradiation physiotherapy ＋ tinidazole injection enema triple therapy, while the traditional Chinese medicine group was given traditional Chinese medicine plus Chinese medicine hot compress and Chinese medicine enema triple therapy. Results： After treatment, the levels of TNF-a, CRP, IL-1beta and IL-6 in western medicine group and Chinese medicine group were signiflcantly lower than those before treatment （P〈0.05）. After treatment, the levels of TNF-a, CRP, IL-1beta and IL-6 in Chinese medicine group were signiflcantly lower than those in western medicine group （P〈0.05）. The erythrocyte sedimentation rate, whole blood high shear viscosity and whole blood low shear viscosity were signiflcantly lower than those before treatment （P〈0.05）. After treatment, the hematocrit, erythrocyte sedimentation rate, whole blood high shear viscosity and whole blood low shear viscosity in TCM group were signiflcantly lower than those in western medicine group （P〈0.05）. Conclusion： TCM triple therapy can effectively improve the hemorheological indexes of patients with chronic pelvic inflammatory disease, alleviate the inflammatory reaction of patients, and increase the clinical value.
作者
吴飞华
WU Fei-hua(Department of gynaecology, Jiangxi Provincial Hospital of traditional Chinese medicine, Nanchang Jiangxi 330006,China)
出处
《药品评价》
CAS
2018年第20期52-54,64,共4页
Drug Evaluation
关键词
中药内服
中药热敷
中药灌肠
慢性盆腔炎
炎性指标
血液流变学
Chinese medicine Orally
Chinese Medicine hot Compress
Chinese Medicine Enema
Chronic Pelvic Inflammation
Inflammatory Indicators
Hemorheology
