摘要
目的研究异甘草酸镁治疗酒精性脂肪肝高转氨酶血症的效果。方法选取2016年11月至2017年11月在我院进行诊治的60例酒精性脂肪肝高转氨酶血症患者,根据治疗方式的不同分为对照组与研究组,各30例。对照组采用常规治疗方式,研究组在对照组基础上加用异甘草酸镁治疗。比较两组患者的疗效。结果治疗后,两组TBIL、AST、ALT、DBIL水平均随着时间延长而显著降低,且研究组均显著低于对照组(P<0.05)。研究组治疗总有效率高于对照组(P<0.05),研究组不良反应总发生率低于对照组(P<0.05)。结论通过对酒精性脂肪肝高转氨酶血症患者实施异甘草酸镁治疗,能够有效改善患者临床症状,并降低其各项肝功能指标,值得临床进一步研究。
Objective To study the effect of magnesium isoglycyrrhizinate in the treatment of high aminotransferase inalcoholic fatty liver. Methods Sixty patients with high aminotransferase in alcoholic fatty liver treated in our hospital fromNovember 2016 to November 2017 were selected and divided into control group and study group according to differenttreatment methods. The control group received conventional treatment. The study group was treated with magnesiumisoglycyrrhizinate on the basis of the control group. The effects of the two groups were compared. Results After treatment,the levels of TBIL, AST, ALT and DBIL in the two groups significantly decreased as time prolonged, and those indexes inthe study group were significantly lower than the control group （P〈0.05）. The total effective rate of treatment in the studygroup was significantly higher than that in the control group（P〈0.05）. The total incidence of adverse reactions in the studygroup was significantly lower than that in the control group （P〈0.05）. Conclusion The implementation of magnesiumisoglycyrrhizinate in patients with high aminotransferase in alcoholic fatty liver can effectively improve the clinicalsymptoms of patients and reduce their liver function indicators. It is worth further studying in clinic.
作者
张波
胡正康
ZHANG Bo;HU Zheng-kang(Yulin No.2 Hospital,Yulin 719000;Hanbin District Third People＇s Hospital,Ankang 725018,China)
出处
《临床医学研究与实践》
2018年第29期30-31,共2页
Clinical Research and Practice
关键词
异甘草酸镁
酒精性脂肪肝
高转氨酶血症
magnesium isoglycyrrhizinate
alcoholic fatty liver
high aminotransferase
