摘要
目的探讨液基薄层细胞制片技术在胸腹水癌细胞检测中的应用价值。方法以2017年1月—2018年1月该院临床科室送检的605份腹水标本为研究对象,全部标本均制作成薄层涂片行液基薄层细胞学检查,同时制作传统涂片行常规细胞学检查,对比观察两种涂片细胞学检查诊断胸腹水癌细胞的检出情况。结果胸腹水标本液基薄层涂片细胞学检查诊断癌细胞阳性表达96份,阳性检出率15.86%,胸腹水传统涂片细胞学检查诊断癌细胞阳性表达77份,阳性检出率12.73%,比较差异无统计学意义(χ~2=3.681,P<0.05)。结论超薄液基细胞技术是检测胸腹水癌细胞的有效手段,薄层涂片能获得优于传统涂片的诊断效果,但仍有不足,建议联合应用以进一步提高癌细胞检出率,更好的为临床提供指导。
Objective To study the application value of ultrathin liquid based cell technology in the Detection of carcinoma cell in hydrothorax and ascites. Methods 605 pieces of ascites specimens submitted to the clinical department in our hospital from January 2017 to January 2018 were selected as the research objects, and all specimens were made into the thin layer smear for thinprep cytology test, and made into the traditional smear for routine cytological examination, and the test situation of smear cytology in carcinoma cell of hydrothorax and ascites was compared and observed.Results There were 96 pieces of cancer cells with positive expression by the cytology of liquid based thin layer smear of hydrothorax and ascites, and the positive test rate was 15.86%, and there were 77 pieces of cancer cells with positive expression by the cytological examination of traditional smear of hydrothorax and ascites, and the positive test rate was12.73%, and the difference between groups was statistically significant（χ^2=3.681, P〈0.05）. Conclusion The ultrathin liquid based cell technology is an effective means in testing the carcinoma cell of hydrothorax and ascites, and the diagnosis effect of thin layer smear is better than that of traditional smear, with disadvantages, and the combined application can be suggested to further improve the cell test rate thus better providing clinical guidance.
作者
闫敢
李明
周蓓蓓
YAN Gan;LIMing;ZHOU Bei-bei(Department of Pathology,Xuyi People＇s Hospital,Xuyi,Jiangsu Province,211700 China)
出处
《系统医学》
2018年第13期12-14,共3页
Systems Medicine
关键词
胸腹水
癌细胞
超薄液基细胞学技术
诊断价值
Hydrothorax and aseites
Cancer cell
Utrathin liquid based cell technology
Diagnostic value
