摘要
肝衰竭是多种因素引起的严重肝损伤,感染是肝衰竭发生发展过程中最常见的并发症之一。肝衰竭患者合并感染病死率显著升高,是临床一线工作者面临的棘手问题。目前肝衰竭合并感染诊治的临床研究数据不充足,国内外亦无临床诊疗的指导性意见。对肝衰竭合并感染的流行状况、病理生理、诊断和治疗的难点热点进行了梳理总结,以期为临床诊疗提供指导,为进一步深入开展相关临床研究提供方向。
Liver failure is a serious liver damage caused by a variety of factors,and infection is one of the most common complications in the development and progression of liver failure. Liver failure patients with infection have a significant increase in mortality,which is a difficult clinical event for physicians. At present,there are no sufficient clinical data on the diagnosis and treatment of liver failure with infection,and there is also a lack of guidelines for clinical diagnosis and treatment in China and foreign countries. This article summarizes the difficulties and hotspots in the prevalence,pathophysiology,diagnosis,and treatment of liver failure with infection,in order to provide guidance for clinical diagnosis and treatment and directions for further clinical research.
作者
陈广
陈韬
宁琴
CHEN Guang;CHEN Tao;NING Qin(Department and Institute of Infectious Diseases,Tongji Hospital,Tongji Medical College of Huazhong University of Technology and Science,Wuhan 430030,China)
出处
《临床肝胆病杂志》
CAS
北大核心
2018年第9期1842-1846,共5页
Journal of Clinical Hepatology
关键词
肝功能衰竭
感染
诊断
治疗学
liver failure
infection
diagnosis
therapeutics
