摘要
目的了解南阳市手足口病患儿病情重症化的相关危险因素,为临床治疗及预防护理措施实施提供借鉴。方法对2016年3月至2017年5月南阳市中心医院收治的94例重症手足口病病例和337例普通手足口病例临床资料进行回顾性分析,行非匹配病例对照研究,运用统计学软件对研究数据进行Logistic回归分析。结果单因素Logistic回归分析结果显示,初次就医单位级别、首诊诊断、发病至就诊间隔时间≥3d、精神状态、体温、发热持续时间≥3d、临床表现等因素与手足口病病情重症化关系密切(P<0.01)。多因素Logistic回归分析结果显示,发病至就医间隔时间≥3d(P<0.01)、持续发热时间≥3d(P<0.01),体温高于38.5°C(P<0.01),精神状态差(P<0.05),频繁呕吐甚至抽搐(P呕吐<0.01,P抽搐<0.05)是手足口病患儿病情重症化的主要危险因素。结论南阳市2016、2017年手足口病患儿病情重症化的主要相关危险因素为:体温≥38.5℃、发热持续≥3d、发病至就医间隔≥3d、呕吐、抽搐、精神状态差。
Objective To understand the relative risk factors for severe hand,foot and mouth disease in Nanyang city,so as to provide reference for clinical treatment and preventive nursing measures. Methods The clinical data of 94 cases of severe hand,foot and foot disease and 337 cases of common hand,foot and mouth cases treated in Nanyang Central Hospital from March 2016 to May 2017 were analyzed. Non matched case-control studies were conducted, and statistical software was used to analyze the data by logistic regression analysis. Results The results of single factor logistic regression analysis showed that the primary medical unit level,the first diagnosis,the onset time interval of more than 3 d,the mental state, the temperature, the duration of fever more than 3 d,and the clinical manifestations were closely related to the severity of the hand,foot and mouth disease （ P〈0.01）. The results of multiple factor logistic regression analysis showed that the onset time interval was more than 3d （ P〈0.01） ,the duration of continuous fever was more than 3 d （ P〈0.01） ,the body temperature was higher than 38.5 degree C （ P〈0.01） ,the mental state was poor （ P〈0.05） ,frequent vomiting and even convulsions （ P vomiting〈0.01, P convulsion 〈0.05） were the main risk factors among the patients with severe hand,foot and foot disease. Conclusion The risk factors for the severity of hand foot and mouth disease in Nanyang city in 2016 and 2017 are body temperature above 38.5 ,fever more than 3 d,onset to medical interval more than 3 d, vomiting, convulsion and poor mental state.
作者
白婷
吴宗跃
BAITing;WU Zong-yue(Nanyang City Central Hospital,Nanyang,Henan,473000,China)
出处
《预防医学论坛》
2018年第5期354-356,364,共4页
Preventive Medicine Tribune
关键词
手足口病
病情重症化
危险因素
Hand
foot and mouth disease
Severe illness
Risk factors
